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Abstract

The compounds 4a-m (functionalized chromene phenyl pyarazolone derivatives) were synthesized using ultrafine zirconia nanoparticles (ZrO2 NPs) by multi-component approach in water-ethanol as green solvent. Zirconia nanoparticles gave good catalytic activity for first four cycles of synthesized product. The structural and morphological characterizations of the as-prepared ZrO2 nanoparticles were performed by using X-ray diffraction, Fourier transform infrared spectroscopy, energy dispersive X-ray microanalysis (EDS) spectroscopy and Ultraviolet visible (UV-visible) absorption spectroscopy. The morphological property revealed the formation of nanoscale particles. In this investigation we gave emphasis on the eco-friendly synthesis of chromene-phenyl pyrazolones derivatives using ZrO2 nanoparticles and water-ethanol. The expected results reveals the applicability of tuneable catalytic activity, reaction time and the reusability of ZrO2 nanoparticles even after several cycles.

Keywords

ZrO2 nanoparticles Green solvent Multi-component Chromene phenyl pyarazolones.

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A. Jadhav, S., V. Raut, A., Farooqui, M., Shinde, B., P. Sarkate, A., & K. Pardeshi, R. (2016). Zirconia Nanoparticles Catalyzed Multi- Component Synthesis of Functionalized Chromene-pyarazolone Derivatives. Asian Journal of Organic & Medicinal Chemistry, 1(3), 91–96. https://doi.org/10.14233/ajomc.2016.AJOMC-P27
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