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Abstract
A new chiral charge transfer (CT) complexes of Schiff base derived from camphor and o-aminophenol with π-acceptor as quinol and vacant orbital acceptor as ZnCl2 have been synthesized and characterized. The IR spectra, X-ray, mass, atomic absorption spectrometry, conductivity and elemental analysis are used to elucidate the structure of the charge transfer complexes. The antioxidant activity was measured for the new chiral charge transfer complexes using free radical scavenging 2-diphenyl-1-picryl-hydrazyl (DPPH) assay. The values of IC50 were as follows: 4.04 ± 0.01 and 0.81.5 ± 0.004 µg/mL for Schiff basequinol and Schiff-ZnCl2, respectively. The IC50 of ascorbic acid was 6.45 ± 0.30 µg/mL. In addition, the antibacterial activity against three bacterial strains, Escherichia coli, Staphylococcus aureus and Streptococcus pneumonia, was examined using agar disc diffusion method. The antibacterial activity was enhanced in the following order: ZnSchiff > quinol-Schiff > Schiff-base.
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References
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References
A. Kokkinou, F. Tsorteki, M. Karpusas, A. Papakyriakou, K. Bethanis and D. Mentzafos, Carbohydr. Res., 345, 1034 (2010); https://doi.org/10.1016/j.carres.2010.03.020.
I.H.T. Al-Karkhi, A.K. Yaseen and H.T. Sadeq, Baghdad Sci. J., 10, 607 (2013).
Y.M. Issa, A.L. El Ansary, O.E. Sherif and H.B. Hassib, Spectrochim. Acta A Mol. Biomol. Spectrosc., 79, 513 (2011); https://doi.org/10.1016/j.saa.2011.03.022.
A.A. Asmaa, Int. J. Eng. Innov. Technol., 5, 12 (2015).
H.H. El-Daroti, S.A. Gadir, M.S. Refat and A.A. Adam, Int. J. Electrochem. Sci., 8, 5774 (2013).
M. El-Batouti, E.H. El-Mossalamy and N.F. Al-Harby, Asian J. Chem., 27, 2719 (2015); https://doi.org/10.14233/ajchem.2015.18878.
W. Chen, I. Vermaak and A. Viljoen, Molecules, 18, 5434 (2013); https://doi.org/10.3390/molecules18055434.
A.M. Adam, M.S. Refat, T. Sharshar and Z.K. Heiba, Spectrochim. Acta A, 95, 458 (2012); https://doi.org/10.1016/j.saa.2012.04.024.
M. Hamming and N. Foster, Interpretation of Mass Spectra of Organic Compounds, Academic Press: New York, USA (1972).
K. Nakamoto, Infrared and Raman Spectra of Inorganic and Coordination Compounds, Parts A and B, John Wiley & Sons, New York (1997).