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Abstract

A hexachlorocyclotriphosphazene (HCCP) catalyzed new method has been developed for the synthesis of 2,3-dihydro-1H-1,5-benzodiazepines by cyclocondensation of o-phenylenediamine with aromatic aldehydes or ketones in acetonitrile at room temperature. This protocol is developed as a clean and safe method utilizing environmentalfriendly and highly efficient catalyst.

Keywords

Hexachlorocyclotriphosphazene o-Phenylenediamine Aromatic aldehydes/ketones Acetonitrile 2,3-Dihydro-1H-1,5-benzodiazepines

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Sharda, S., Prasad, D. N., Kumar, S., & K. Singh, R. (2018). Hexachlorocyclotriphosphazene Catalyzed One-Pot Multicomponent Synthesis of 2,3-Dihydro-1H-1,5-benzodiazepines. Asian Journal of Organic & Medicinal Chemistry, 3(4), 176–180. https://doi.org/10.14233/ajomc.2018.AJOMC-P151
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References

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