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Abstract

A simple, selective, accurate and low-cost spectrophotometric method has been described for determination of satranidazole in bulk and pharmaceutical formulations. The developed method involves the formation of chloroform extractable colored ion-association complex of satranidazole with Tropaeolin OOO (TPooo). The extracted colored complex showed absorbance maximum at wavelength 484 nm and obeying Beer′s law in the concentration 4-20 μg mL-1 with the correlation coeffiecent of 0.9998. The results of statistical analysis of the proposed method reveals high accuracy and good precession. Thus, the proposed method can be used commercially for the determination of satranidazole in bulk and pharmaceutical formulations.

Keywords

Satranidazole Ion-Associative complex Tropaeolin OOO Validation Visible spectrophotometry

Article Details

How to Cite
Kiran Kumar, K., Nadh, R., Siva Kishore, M., & Giri Prasad, G. (2019). Determination of Satranidazole through Ion-Associative Complex Reaction. Asian Journal of Organic & Medicinal Chemistry, 4(1), 23–27. https://doi.org/10.14233/ajomc.2019.AJOMC-P166
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