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Abstract

To achieve an efficient synthesis of some novel α-aminophosphonates via Pudovik reaction; ultrasonic irradiation has been adopted. Major benefits of this method is eco-friendly, free of catalyst, high yielding, uncomplicated work-up procedure, short reaction time and solvent free condition. Spectral characterization and elemental analysis of the synthesized samples was carried out. In vitro antioxidant activity of the synthesized a-aminophosphonates compounds was screened by DPPH•, O2•− and NO• scavenging methods. Good to moderate activities were shown by most of the compounds while compared with the standards.

Keywords

α-Aminophosphonates Ultrasonic irradiation Antioxidant activity.

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Copyright (c) 2018 Asian Journal of Organic & Medicinal Chemistry

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Singh1, A., Singh1, P., Srivastava2, N., Verma3, S., Singh4, A., & Kumar Srivastava5, A. (2022). Ultrasound-Promoted Solvent-Free Synthesis of Some New α-Aminophosphonates as Prospective Antioxidants. Asian Journal of Organic & Medicinal Chemistry, 3(4), 208–213. https://doi.org/10.14233/ajomc.2018.AJOMC-P358
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