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Abstract

Polyethylene glycol (PEG) was found to be an effective and nontoxic reaction medium for the one-pot synthesis of functionalized pyrroles under catalyst-free conditions in excellent yields. Environmental acceptability, low cost, high yields and recyclability of the PEG are the important features of this protocol.

Keywords

Functionalized pyrroles Amines Aromatic aldehydes and Nitroalkanes Polyethylene glycol 1,3-Dicarbonyl compounds Catalyst-free conditions

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Ramesh, P., & Bhaskar, K. (2016). Polyethylene Glycol (PEG-400) as an Efficient and Recyclable Reaction Medium for Four-Component Coupling One-Pot Synthesis of Functionalized Pyrroles under Catalyst-free Conditions. Asian Journal of Organic & Medicinal Chemistry, 1(2), 61–65. https://doi.org/10.14233/ajomc.2016.AJOMC-P18
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