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Abstract

The present investigation reports design of a new pH responsive polymeric material from shellac for pharmaceutical applications. The material was prepared from the combination of shellac and glycine. Acrylic acid was used to incorporate pH responsive characteristics in the material. The material was characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis and scanning electron micrograph techniques. The thermal stability and the kinetics of material decomposition were evaluated using various mathematical models. The kinetics of controlled release of 5-amino salicylic acid was studied in buffer medium using Fick’s model equation.

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Shellac Glycine pH responsive Controlled release 5-Amino salicylic acid

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Barik, A., Patnaik, T., Parhi, P., & Dey, R. (2016). pH Responsive Shellac for Pharmaceutical Applications: Preparation, Thermal Stability and Controlled Release of 5-Amino salicylic Acid. Asian Journal of Organic & Medicinal Chemistry, 1(2), 45–50. https://doi.org/10.14233/ajomc.2016.AJOMC-P8
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