Main Article Content
Abstract
The present study aimed to standardize the crude drug from ‘Euphorbia prostrata’ by doing qualitative and quantitative analysis of plant pulverized parts and extracts. Physico-chemical analysis such as moisture content, total ash, water insoluble ash, sulphated ash, acid insoluble ash and water and alcohol extractives was done on powdered raw material. The moisture content and ash values were found within the recommended range (moisture content 5 % and ash value 10.5 %). The value of water soluble extract was higher as compared to acid soluble extractives. Percentage yield was found to be highest in methanolic solvent. The phytochemical analysis i.e. total lipids, total proteins and carbohydrates of crude powder showed that lipids and proteins contents were high.
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References
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References
A. Pandey and S. Tripathi, J. Pharmacogn. Phytochem., 2, 115 (2014).
N. Dubey, R. Kumar and P. Tripathi, Curr. Sci. (India), 86, 37 (2004).
A. Longanga Otshudi, A. Vercruysse and A. Foriers, J. Ethnopharmacol., 71, 411 (2000); https://doi.org/10.1016/S0378-8741(00)00167-7.
G.L. Webster, Clin. Dermatol., 4, 36 (1986); https://doi.org/10.1016/0738-081X(86)90062-3.
M.U. Saeed-ul-Hassan, Afr. J. Pharm. Pharmacol., 7, 2321 (2013); https://doi.org/10.5897/AJPP12.1027.
M. Milovic and M. Randic, Natura Croat., 10, 89 (2001).
S.M. Mishra, A. Pathak and P.K. Sharma,
S.K. Sharma, J. Singh and S. Singh, Int. J. Pharm. Sci. Res., 3, 1043 (2012).
G.D. Bakhshi, D.G. Langade and V.S. Desai, Bombay Hosp. J., 50, 577 (2008).
U.S. Pharmacopeial Convention, vol. 32 (2009).
U. Saleem, K. Hussain, M. Ahmad, N.I. Bukhari, A. Malik and B. Ahmad, Pak. J. Pharm. Sci., 27, 577 (2014).
O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, J. Biol. Chem., 193, 265 (1951).
S. Al-Hooti, J.S. Sidhu and H. Qabazard, J. Food Sci. Technol., 35, 44 (1998).
H. Usman, F.I. Abdulrahman and A. Usman, Afr. J. Trad. Complement. Altern. Med., 6, 289 (2009).
H.P. Chhetri, N.S. Yogol, J. Sherchan, K. Anupa, S. Mansoor and P. Thapa, Kathmandu Univ. J. Sci. Eng. Technol., 4, 49 (2008).
N. Savithramma, M.L. Rao and D. Suhrulatha, Middle East J. Sci. Res., 8, 579 (2011).
F. Mojab, M. Kamalinejad, N. Ghaderi and H.R. Vahidipour, Iran. J. Pharm. Res., 2, 77 (2010).
M. Qaisar, S.N. Gilani, S. Farooq, A. Rauf, R. Naz, Shaista and S. Perveez, Am.- Eur. J. Agric. Environ. Sci., 12, 1056 (2012). https://doi.org/10.5829/idosi.aejaes.2012.12.08.1798.
I. Ajayi, O. Ajibade and R. Oderinde, Res. J. Chem. Sci., 1, 58 (2011).
A. Manjamalai, R.S.S. Singh, C. Guruvayoorappan and V.B. Grace, Global J. Biotechnol. Biochem., 5, 120 (2010).
K. Hussain, Z. Ismail, A. Sadikun and P. Ibrahim, Nat. Prod. Radiance, 7, 402 (2008).
D. Heimler, P. Vignolini, M.G. Dini, F.F. Vincieri and A. Romani, Food Chem., 99, 464 (2006); https://doi.org/10.1016/j.foodchem.2005.07.057.
K. Slinkard and V.L. Singleton, Am. J. Enol. Vitic., 28, 49 (1977).
K.C. Waterman and R.C. Adami, Int. J. Pharm., 293, 101 (2005); https://doi.org/10.1016/j.ijpharm.2004.12.013.
World Health Organization, Quality Control Methods for Medicinal Plant Materials, Geneva, pp. 28-29 (1998).
K.R. Brain and T.D. Turner, The Practical Evaluation of Phytopharma-ceuticals, Wright-Scientechnica Bristol (1975).
O.A. Ekpete, S.E. Onisogen and E.P. Fubara, Br. J. Appl. Sci. Technol., 3, 1447 (2013); https://doi.org/10.9734/BJAST/2014/4431.
N.A. Imaga, G.O. Gbenle, V.I. Okochi, S. Adenekan, T. Duro-Emmanuel, B. Oyeniyi, P.N. Dokai, M. Oyenuga, A. Otumara and F.C. Ekeh, Sci. Res. Essays, 5, 2201 (2010).
P. Njoku and M. Akumefula, Pak. J. Nutr., 6, 613 (2007); https://doi.org/10.3923/pjn.2007.613.615.
J. Mbadianya, B. Echezona, K. Ugwuoke and R. Wokocha, OSR J. Agric. Vet. Sci., 2, 51 (2013).
R. Okigbo, C. Anuagasi and J. Amadi, J. Med. Plants Res., 3, 86 (2009).
D. Enyiukwu, A. Awurum, C. Ononuju and J. Nwaneri, Int. J. Adv. Agric. Res., 2, 8 (2014).
K. Salna, K. Sreejith, M. Uthiralingam, A.P. Mithu, M.J. Milton and T.F. Albin, Int. J. Pharm. Pharm. Sci., 3, 291 (2011).