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Abstract

A greener method for the conjugate addition of amines to conjugated alkenes via aza-Michael reaction under the influence of water extract of the biocatalyst derived of Musa balbisiana (Colla) was developed. Reaction yields was excellent at room temperature where several amines to α,β-unsaturated ketones, esters (specially Baylis-Hillman adducts) and nitriles has been carried out efficiently in water. Bio-catalysts used in the reaction can be reused for several times. Bis-product formation can be controlled by varying the ratio of substrates in this environmentally benign procedure, which has provided clean formation of the products with good selectivity.

Keywords

Aza-Michael Biocatalyst Musa balbisiana (Colla). b-Aminocarbonyl b-Aminonitrile

Article Details

How to Cite
Saikia, M., Das, P., & C. Deka, D. (2017). Synthesis of β-Aminocarbonyl and β-Aminonitrile Compounds Catalyzed byWater Extract of Musa balbisiana (Colla) via Aza-Michael Reaction. Asian Journal of Organic & Medicinal Chemistry, 2(4), 138–142. https://doi.org/10.14233/ajomc.2017.AJOMC-P77

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