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Abstract

Aminoalkylation of vanillin (4-hydroxy-3-methoxybenzaldehyde) was achieved by reactions of vanillin with formaldehyde and suitable amine in acetonitrile. The products aminoalkyalted vanillin compounds 1-5 were purified by column and thin layer chromatography and identified by spectroscopic methods viz. UV, IR, NMR and mass spectrometry.

Keywords

Vanllin Aminoalkyation Formaldehyde Acetonitrile

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E.M. Noreljaleel, A., M.A. Fadul, H., H. van der Westhuizen, J., Abdel Karim, M., M.H. Ayuob, S., & Abualreish, M. (2018). Synthesis and Structural Elucidation of 4-Hydroxy-3-methoxy-5- aminomethylbenzaldehydes. Asian Journal of Organic & Medicinal Chemistry, 3(2), 50–53. https://doi.org/10.14233/ajomc.2018.AJOMC-P124
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