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Abstract

4-Hydrazinylpyrrolo[2,3-d]pyrimidines (1) have been reacted with different condensing reagents such as ethyl-2-methoxy acrylate and ethyl acetoacetate with and without the support of Montnorillonite K-10 to form respective 4-pyrazolylpyrrolopyrimidines (3 and 5) of synthetic and biological interests, where Montnorillonite K-10 supported synthesis of compounds 3 and 5 was found to be cleaner and faster.

Keywords

4-Hydrazinylpyrrolopyrimidine 4-N-Pyrazolylpyrrolopyrimidines Ethyl acetoacetate 2-Cyanoethylmethoxy acrylate Montnorillonite K-10

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D. Shah, R., C. Ramani, V., & M. Shah, N. (2018). Montnorillonite K-10 Supported Rapid Synthesis of 4-N-Pyrazolylpyrrolopyrimidines. Asian Journal of Organic & Medicinal Chemistry, 3(3), 102–106. https://doi.org/10.14233/ajomc.2018.AJOMC-P134
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