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Abstract

3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding chalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a library of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphatewater biphasic system at ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are immiscible, has been easily recycled and reused after separation of the products without any noticeable diminution in its activity.

Keywords

Cyclopropyl Pyrazole ([bmim][PF6]) Biphasic Antifungal activity

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Burde, P., & Rahatgaonkar, A. (2019). Facile Synthesis and Biological Evaluation of Cyclopropyl-Pyrazole Hybrids in [bmim][PF6]- Water Biphasic System as Antifungal Agents. Asian Journal of Organic & Medicinal Chemistry, 4(3), 152–158. https://doi.org/10.14233/ajomc.2019.AJOMC-P192
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