Preparation and Characterization of Hydrophobic Alginate Derivative Nanocapsules Entrapping l-Cyhalothrin
Corresponding Author(s) : Qiang Lin
Asian Journal of Chemistry,
Vol. 25 No. 17 (2013): Vol 25 Issue 17 page 9904-9908
Hydrophobic alginate derivative was synthesized by the amidation of alginate and octylamine. The generated octyl-grafted alginate-amide was confirmed by FTIR and 1H NMR. The degree of substitution was 0.23 and whose critical aggregation concentration in aqueous medium was 0.34 mg/mL. This strategy of nanocapsule formulation was based on microemulsion template with octyl-grafted alginate-amide derivative. The morphology and the size of nanocapsules were characterized by transmission electron microscopy, whose average size is 25.78 nm. The nanocapsule has a high loading efficiency valve of 99.95 %. The release characteristics of the nanocapsules were evaluated in methanol and the results indicated that the nanocapsules restrained the release of l-cyhalothrin.
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