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Vol. 38 No. 1 (2026): Vol 38 Issue 1, 2026

Copyright (c) 2025 Bhuwan Chandra, G. LOHIYA, J. KOHLI, A. TAMTA, N.D. KANDPAL

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Biosynthesis of Rice Starch-Manganese Dioxide (IV) Nanocomposite: Its Characterization and Biological Potential

Synthesis of Rice starch-MnO2 nanocomposite
https://doi.org/10.14233/ajchem.2026.34994
Geetanjali
Department of Chemistry, Kumaun University Nainital, S.S.J. Campus Almora-263601, India
https://orcid.org/0000-0002-6168-6806
B. Chandra
Department of Chemistry, Kumaun University Nainital, S.S.J. Campus Almora-263601, India
https://orcid.org/0000-0001-7413-5037
J. Prasad
Department of Chemistry, Government Post Graduate College (Affiliated to Kumaun University), Sitarganj-262405, India
https://orcid.org/0009-0007-8025-3436
A. Tamta
Department of Chemistry, S.S.H.D. Government Degree College Agrora (Affiliated to Sri Dev Suman Uttarakhand University), Dharmandal, Tehri Garhwal-249127, India
https://orcid.org/0000-0003-2214-1210
N.D. Kandpal
Department of Chemistry, Kumaun University Nainital, S.S.J. Campus Almora-263601, India
https://orcid.org/0000-0002-0477-0200

Corresponding Author(s) : B. Chandra

bc_physical@rediffmail.com

Asian Journal of Chemistry, Vol. 38 No. 1 (2026): Vol 38 Issue 1, 2026

Abstract

Manganese dioxide (MnO2) nanoparticles were biosynthesized in this study, utilizing rice starch (a natural polymer) to form nanocomposites with useful biological and analytical properties. The synthesized nanocomposites were characterized by XRD, FTIR, UV-Vis, HRTEM, FESEM-EDX and Zeta potential analysis. FTIR confirmed the formation of rice starch-manganese dioxide (rice starch-MnO2) nanocomposites and the presence of functional groups in the synthesis. XRD analysis determined the average crystalline size to be 38.27 nm, while FESEM and HRTEM revealed a spherical structure with irregular morphology. EDX confirmed a presence of manganese content 43.12%, oxygen 29.02% and carbon 27.86%. The anticancer activity against the HepG2 cell line (a human liver cancer cell line) was determined by MTT Assay, with an IC50 value of 76.31 ± 0.092 µg/mL. Antioxidant activity shows appreciable potency in the DPPH scavenging assay. The nanocomposites were thought to be stable under thermal conditions and to have prominent antioxidant and anticancer properties.

Keywords

Rice starch-MnO2 nanocomposite Nanoparticles Anticancer activity Antioxidant activity
(1)
Geetanjali; Chandra, B.; Prasad, J.; Tamta, A.; Kandpal, N. Biosynthesis of Rice Starch-Manganese Dioxide (IV) Nanocomposite: Its Characterization and Biological Potential: Synthesis of Rice Starch-MnO2 Nanocomposite. ajc 2025, 38, 173-179.
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