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Vol. 38 No. 1 (2026): Vol 38 Issue 1, 2026

Copyright (c) 2025 Ghulam Murtaza Arain

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Groundwater Fluoride Contamination in Balochistan, Pakistan: Health Risk and Regional Variability Analysis using HQ and NPI Indices

https://doi.org/10.14233/ajchem.2026.34804
Ghulam Murtaza Arain
Pakistan Council of Research in Water Resources, Main University Road, Karachi, Pakistan
https://orcid.org/0000-0002-6998-2896
Nazia Sattar
Pakistan Council of Research in Water Resources, Main University Road, Karachi, Pakistan
https://orcid.org/0009-0008-9214-0719
Sumaira Khatoon
Centre of Excellence in Marine Biology, University of Karachi, Karachi, Pakistan
https://orcid.org/0000-0001-6385-7034
Sadaf Naseem
Department of Geology, University of Karachi, Karachi, Pakistan
https://orcid.org/0009-0004-2580-191X
Shakeel Badshah
Pakistan Council of Research in Water Resources, Islamabad, Pakistan
https://orcid.org/0009-0002-3681-1705

Corresponding Author(s) : Ghulam Murtaza Arain

drmurtaza1977@gmail.com

Asian Journal of Chemistry, Vol. 38 No. 1 (2026): Vol 38 Issue 1, 2026

Abstract

Groundwater fluoride contamination in Balochistan, Pakistan, poses significant public health and socio-economic challenges. This study comprehensively assessed groundwater quality across 7 districts, including Quetta, Loralai, Sibi, Kachi Bolan, Sohbatpur, Jafarabad and Naseerabad, through 825 samples collected during 2022 and 2023. Parameters analyzed included fluoride (F–), total dissolved solids (TDS), electrical conductivity (EC) and pH. Advanced indices, including hazard quotient (HQ), fluoride concentration (CF), pollution index (PIF) and Nemerow Pollution Index (NPI), were used to evaluate risks for male and female population groups. The highest F– contamination was observed in Sibi (58% unsafe samples), followed by Loralai (20.2%), with contamination severity ranked as Sibi > Loralai > Sohbatpur > Kachi Bolan > Quetta > Jafarabad > Naseerabad. HQ analysis revealed children are significantly more vulnerable, with the highest HQ for children observed in Sohbatpur (mean: 1.128). The CF analysis showed minimal risk for infants (< 1 year) but higher exposure for children (1-8 years), particularly in Sibi (mean: 0.112 mg/L). The NPI findings classified Nasirabad as minimal risk (NPI: 0.859), while Sibi, Sohbatpur, Kachi Bolan and Loralai posed high risks (NPI: 1.33-1.50), whereas EC and TDS variability highlighted groundwater quality differences, with high salinity and TDS concentrations in Sohbatpur and Jafarabad indicating unsuitability for drinking.

Keywords

Groundwater Toxicity Hazard quotient Nemerow Pollution Index Children’s vulnerability Balochistan Pakistan
(1)
Arain, G. M.; Sattar, N.; Khatoon, S.; Naseem, S.; Badshah, S. Groundwater Fluoride Contamination in Balochistan, Pakistan: Health Risk and Regional Variability Analysis Using HQ and NPI Indices. ajc 2025, 38, 123-132.
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References
  1. S. Ayoob and A.K. Gupta, Crit. Rev. Environ. Sci. Technol., 36, 433 (2006); https://doi.org/10.1080/10643380600678112
  2. A.M. MacDonald, H.C. Bonsor, B.É.Ó. Dochartaigh and R.G. Taylor, Environ. Res. Lett., 7, 024009 (2012); https://doi.org/10.1088/1748-9326/7/2/024009
  3. WHO, Guidelines for Drinking-Water Quality, WHO: Geneva, edn. 4, (2011).
  4. S. Naseem, T. Rafique and E. Bashir, Pakistan J. Anal. Chem., 11, 1045 (2010).
  5. M.S. Malkani, Geol. Surv. Pak. Bull., 45, 1 (2012).
  6. T. Rafique, S. Naseem, T.H. Usmani, E. Bashir, F.A. Khan and M.I. Bhanger, J. Hazard. Mater., 171, 424 (2009); https://doi.org/10.1016/j.jhazmat.2009.06.018
  7. A. Akramkhanov and P.L.G. Vlek, Environ. Monit. Assess., 184, 2475 (2012); https://doi.org/10.1007/s10661-011-2132-5
  8. W.M. Edmunds and P.L. Smedley, in eds.: O. Selinus, Fluoride in Natural Waters, In: Environmental Geochemistry, pp. 311-336 (2013).
  9. A.J. Malin and C. Till, Environ. Health, 14, 17 (2015); https://doi.org/10.1186/s12940-015-0003-1
  10. Pakistan Council of Research in Water Resources (PCRWR), National Water Quality Monitoring Program, Government of Pakistan (2007).
  11. T. Rafique, S. Naseem, T.H. Usmani, E. Bashir, F.A. Khan and M.I. Bhanger, Pak. J. Med. Sci., 30, 1165 (2014).
  12. L.O. Daré, P.-E. Bruand, D. Gérard, B. Marin, V. Lameyre, F. Boumédiène and P.-M. Preux, BMC Public Health, 19, 1645 (2019); https://doi.org/10.1186/s12889-019-7933-4
  13. UNICEF, Fluoride in Water: An Overview, UNICEF, New York (1999).
  14. Pakistan Ministry of Climate Change, National Action Plan for Safe Water, Govt. of Pakistan (2018).
  15. A.H. Kazmi and M.Q. Jan, Geology and Tectonics of Pakistan, Graphic Publishers, Pakistan (1997).
  16. A.S. Khan, M.A. Bhatti and M. Noor, J. Pakistan Geogr., 22, 78 (2015).
  17. N. Ahmad, Pak. Dev. Rev., 47, 45 (2008).
  18. S.M.I. Shah, Stratigraphy of Pakistan, Memoirs of the Geological Survey of Pakistan (2009).
  19. S. Ibrahim and M. Zubair, Int. J. Agric., 35, 112 (2018).
  20. R. Zaman, K. Haider and A. Baig, J. Water Resour., 13, 56 (2017).
  21. M.A. Qureshi, K. Mahmood and F. Ali, Pakistan J. Geol., 18, 45 (2002).
  22. M.S. Aftab, Acta Mineral. Pakistanica, 8, 30 (1997).
  23. N. Ahmad, H. Khan and S. Bukhari, Mineral Resources of Loralai District, Geological Survey of Pakistan (2010).
  24. USEPA, Risk Assessment Guidance for Superfund: Vol. I - Human Health Evaluation Manual (Part A), EPA/540/1-89/002, Washington DC (1989).
  25. USEPA, Exposure Factors Handbook: 2011 Edition, EPA/600/R-09/052F, Washington DC (2011).
  26. WHO, Guidelines for Drinking-Water Quality, 3rd Ed., WHO, Geneva (2004).
  27. N.L. Nemerow, Scientific Stream Pollution Analysis, McGraw-Hill, New York (1974).
  28. J. Fawell, K. Bailey, J. Chilton, E. Dahi, L. Fewtrell and Y. Magara, Fluoride in Drinking-Water, WHO, Geneva (2006).
  29. A. Farooqi, H. Masuda and N. Firdous, Environ. Pollut., 145, 839 (2007); https://doi.org/10.1016/j.envpol.2006.05.007
  30. S. Naseem, Ph.D Thesis, Groundwater Quality Assessment for Deter-mining Geogenic Pollution, Contamination and Health Effects in Thatta-Hyderabad Region, Sindh, Department of Geology, University of Karachi, Pakistan, p. 123 (2012).
  31. V.P. Meena, N. Ahmad, R. Singh, A. Vyas, A. Kumar, S. Kumar and M. Kumar, Phys. Chem. Earth Parts ABC, 140, 104029 (2025); https://doi.org/10.1016/j.pce.2025.104029
  32. Y. Ling, J. Podgorski, M. Sadiq, H. Rasheed, S.A.M. Akber, S. Eqani and M. Berg, Sci. Total Environ., 839, 156058 (2022); https://doi.org/10.1016/j.scitotenv.2022.156058
  33. M. Umar, W. Amir, A.M. Kassi, M. Farooq, M.A. Sabir and Faridullah, Global NEST J., 16, 938 (2014).
  34. L. Wang, J. Wang, L. Zhu and J. Wang, Environ. Geochem. Health, 40, 763 (2018); https://doi.org/10.1007/s10653-017-0022-7
  35. A.M. Ellahi, Assessment of Fluoride in Drinking Water and its Correlation with Different Physicochemical Parameters in the Selected Areas of Quetta, Pakistan, Pakistan Science Foundation/PASTIC, Islamabad, pp. 1–XX (2018).
  36. M.A. Tahir and H. Rasheed, Drink. Water Eng. Sci., 6, 17 (2013); https://doi.org/10.5194/dwes-6-17-2013
  37. A.D. Mohammad, R. Faisal and M.M. Akhtar, Pak. J. Anal. Environ. Chem., 21, 314 (2020).
  38. R. Ullah, S. Muhammad and I.A.K. Jadoon, Microchem. J., 147, 115 (2019); https://doi.org/10.1016/j.microc.2019.04.053
  39. A. Rasool, A. Farooqi, T. Xiao, W. Ali, S. Noor, O. Abiola, S. Ali and W. Nasim, Environ. Geochem. Health, 40, 1265 (2018); https://doi.org/10.1007/s10653-017-0054-z
  40. A. Ayub and S.S. Ahmad, Sustainability, 12, 6889 (2020); https://doi.org/10.3390/su12176889
  41. H. Rasheed, F. Altaf, K. Anwaar and M. Ashraf, Drinking Water Quality in Pakistan: Current Status and Challenges, Pakistan Council of Research in Water Resources (PCRWR), Islamabad, pp. 141 (2021).
  42. A. Raza, N.R. Syed, R. Fahmeed, S. Acharki, S. Hussain, M. Zubair, H. Almohamad, J.O. Alao, M.N. Rahman and H.G. Abdo, SN Appl. Sci., 5, 297 (2023); https://doi.org/10.1007/s42452-023-05520-7
  43. T.A. Chandio, M.N. Khan and A. Sarwar, Environ. Monit. Assess., 187, 531 (2015); https://doi.org/10.1007/s10661-015-4753-6
  44. S. Afzal, S. Durrani, A.K. Malghani, M. Khan, N. Sajjad and N. Tariq, Pak. J. Nutr., 15, 85 (2016); https://doi.org/10.3923/pjn.2016.85.88
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