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Vol. 34 No. 11 (2022): Vol 34 Issue 11, 2022

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A Greener, Versatile and Convenient Approach for Catalyst Free Conversion of Pyrazole Aldehydes into Carbonitriles

https://doi.org/10.14233/ajchem.2022.23957
Selvaraj Jayanthi
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi613503, India
Manickam Pramesh
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi613503, India
Periyasamy Monisha
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi613503, India
Moorthy Vetriselvan
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi613503, India
Ragunathan Venkatachalam
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi613503, India

Corresponding Author(s) : Ragunathan Venkatachalam

mprameshchemistry@gmail.com

Asian Journal of Chemistry, Vol. 34 No. 11 (2022): Vol 34 Issue 11, 2022

Abstract

A new, efficient and catalyst-free synthetic strategy was developed for ten carbonitriles by the combination of pyrazole aldehydes and hydroxylamine hydrochloride in the presence of green solvent-glycerol. All the synthesized carbonitriles were confirmed from by 1H, 13C NMR and high resolution mass spectroscopies. The proposed synthetic process was simple, effective with high product yields and environmentally benign with mild reaction conditions.

Keywords

Carbonitriles Hydroxylamine hydrochloride Glycerol Pyrazole aldehyde
Jayanthi, S., Pramesh, M., Monisha, P., Vetriselvan, M., & Venkatachalam, R. (2022). A Greener, Versatile and Convenient Approach for Catalyst Free Conversion of Pyrazole Aldehydes into Carbonitriles. Asian Journal of Chemistry, 34(11), 2887–2890. https://doi.org/10.14233/ajchem.2022.23957
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