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Vol. 32 No. 8 (2020): Vol 32 Issue 8, 2020

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Physico-Chemical and Biocompatibility of Poly(vinyl alcohol): Polyethylene Glycol/κ-Carragreenan Membrane by Freeze-Gelation Method

https://doi.org/10.14233/ajchem.2020.22652
Anand V. Nasalapure
Department of Industrial Chemistry, Mangalore University Mangalgangothri-574199, India
https://orcid.org/0000-0001-7532-0189
Raju Krishna Chalannavar
Department of Applied Botany, Mangalore University Mangalgangothri-574199, India
https://orcid.org/0000-0001-6682-4537
Deepak R. Kasai
Department of Basic Science, School of Engineering and Technology, Jain University, Jakkasandra-562112, India
https://orcid.org/0000-0003-3004-2044

Corresponding Author(s) : Raju Krishna Chalannavar

drrajkc@gmail.com

Asian Journal of Chemistry, Vol. 32 No. 8 (2020): Vol 32 Issue 8, 2020

Abstract

The aim of this study was to fabricate membrane based on poly(vinyl alcohol) (PVA):polyethylene glycol (PEG)/κ-carragreenan (KC) with different weight ratio (w/v) by freeze gelation method. The prepared membrane was characterized by using SEM, FT-IR, TGA, AFM and XRD techniques. The results revealed that FTIR and SEM showed good molecular interaction among the PVA/PEG with κ-carragreenan. The rate of thermal degradation stabilized with increased κ-carragreenan ratio and also increased the percent of crystallinity. Further water  uptake also performed under phosphate buffer saline (PBS) media and results showed increased rate of swelling with increased κ-carragreenan concentration, which enhanced the  stability of water uptake. Moreover cell viability performed using MTT method. The highest compatibility showed for lower concentration κ-carragreenan (PVA/PEG/KC10%). Overall results  exhibited moderate swelling and degradation, good mechanical properties with strong molecular interaction between PVA/PEG with κ-carragreenan these all characters might have advantage in the field of biomedical applications.

Keywords

Poly(vinyl alcohol) Polyethylene glycol κ-Carragreenan Morphology Biocompatibility
Nasalapure, A. V. ., Chalannavar, R. K. ., & Kasai, D. R. . (2020). Physico-Chemical and Biocompatibility of Poly(vinyl alcohol): Polyethylene Glycol/κ-Carragreenan Membrane by Freeze-Gelation Method. Asian Journal of Chemistry, 32(8), 1874–1880. https://doi.org/10.14233/ajchem.2020.22652
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