Copyright (c) 2018 AJC
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Synthesis, Characterization and Pharmacological Activity of Phenoxy Acetic Acid and Pyrazinium Chlorochromate
Corresponding Author(s) : K.K. Ilavenil
Asian Journal of Chemistry,
Vol. 30 No. 10 (2018): Vol 30 Issue 10, 2018
Abstract
This study describes the synthesis and antibacterial, antifungal activity of phenoxy acetic acid and pyrazinium chlorochromate. The compounds were characterized by infrared and ultra violet visible spectral data. These compounds were reviewed for antibacterial and antifungal activity against Streptococcus, Entrococcus, Bacillus cereus, Proteus vulgaris, Mycobacterium tuberculosis, Azotobacter, E. coli, Pseudomonas aeruginosa, Candida albicans, A. niger, Fusarium and Trichoderma by disc diffusion method.
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References
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R. Chawla, U. Sahoo, A. Arora, P.C. Sharma and V. Radhakrishnan, Acta Pol. Pharm. Drug Res., 67, 55 (2010).
A.R. Katritzky, Chem. Rev., 104, 2125 (2004); https://doi.org/10.1021/cr0406413.
M.E. Azab, M.M. Youssef and E.A. El-Bordany, Molecules, 18, 832 (2013); https://doi.org/10.3390/molecules18010832.
K.G. Sekar and G. Manikandan, Oxid. Commun., 35, 577 (2012).
B.H. Asghar, Arab. J. Chem.; https://doi.org/10.1016/j.arabjc.2015.04.006.
H. Foks, D. Pancechowska-Ksepko, A. Kedzia, Z. Zwolska, M. Janowiec and E. Augustynowicz-Kopec, II Farmaco, 60, 513 (2005); https://doi.org/10.1016/j.farmac.2005.05.002.
E. Abignente, Actual Chim. Ther., 18, 193 (1991).
P. Gund and T.Y. Shen, J. Med. Chem., 20, 1146 (1977); https://doi.org/10.1021/jm00219a007.
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M.V. Baldwin, D.A. Sonia, T.J. Sindhu, C. Meena, A.R. Bhar and K. Krishnakumar, World J. Pharm. Pharm. Sci., 3, 1124 (2014).
M. Gür, N. Sener, H. Muglu, M.S. Çavus, O.E. Özkan, F. Kandemirli and I. Sener, J. Mol. Struct., 1139, 111 (2017); https://doi.org/10.1016/j.molstruc.2017.03.019.
K. Nishie, A.C. Waiss Jr. and A.C. Keyl, Toxicol. Appl. Pharmacol., 17, 244 (1970); https://doi.org/10.1016/0041-008X(70)90149-3.
L. Racané, S. Kraljevic Pavelic, I. Ratkaj, V. Stepanic, K. Pavelic, V. TralicKulenovic and G. Karminski-Zamola, Eur. J. Med. Chem., 55, 108 (2012); https://doi.org/10.1016/j.ejmech.2012.07.005.
B.V. Clineschmidt, J.C. McGuffin and A.B. Pflueger, Eur. J. Pharmacol., 44, 65 (1977); https://doi.org/10.1016/0014-2999(77)90117-0.
N. Dias, U. Jacquemard, B. Baldeyrou, A. Lansiaux, J.-F. Goossens, C. Bailly, S. Routier and J.-Y. Mérour, Eur. J. Med. Chem., 40, 1206 (2005); https://doi.org/10.1016/j.ejmech.2005.07.003.
R.S. Kumar, I.A. Arif, A. Ahamed and A. Idhayadhulla, Saudi J. Biol. Sci., 23, 614 (2016); https://doi.org/10.1016/j.sjbs.2015.07.005.
P.P. Lovisolo, G. Briatico-Vangosa, G. Orsini, R. Ronchi, R. Angelucci and G. Valzelli, Pharmacol. Res. Commun., 13, 151 (1981); https://doi.org/10.1016/S0031-6989(81)80016-1.
C.P. Meher, A.M. Rao and Md. Omar, Asian J. Pharm. Sci. Res., 3, 43 (2013).
M. Shahar Yar, A.A. Siddiqui and M.A. Ali, Bioorg. Med. Chem. Lett., 16, 4571 (2006); https://doi.org/10.1016/j.bmcl.2006.06.021.
M. Shahar Yar, M.A. Bakht, A.A. Siddiqui, M.M. Abdullah and E. De Clercq, J. Enzym. Inhib. Med. Chem., 24, 876 (2009); https://doi.org/10.1080/14756360802447917.
M.A. Ali, M.S. Yar, M. Kumar and G.S. Pandian, Nat. Prod. Res., 21, 575 (2007); https://doi.org/10.1080/14786410701369367.
S.N. Mokale, M.C. Nevase, N.S. Sakle, P.N. Dube, V.R. Shelke, S.A. Bhavale and A. Begum, Bioorg. Med. Chem. Lett., 24, 2155 (2014); https://doi.org/10.1016/j.bmcl.2014.03.030.
G. Turan-Zitouni, L. Yurttas, Z.A. Kaplancikli, Ö.D. Can and Ü. Demir Özkay, Med. Chem. Res., 24, 2406 (2015); https://doi.org/10.1007/s00044-014-1309-1.
A. Iqbal, H. Siddiqui, C. Ashraf, M. Ahmad and G. Weaver, Molecules, 12, 245 (2007); https://doi.org/10.3390/12020245.
M. Urban, J. Sarek, M. Kvasnica, I. Tislerova and M. Hajduch, J. Nat. Prod., 70, 526 (2007); https://doi.org/10.1021/np060436d.
M. Kucerova-Chlupacova, M. Dosedel, J. Kunes, M. Soltesova-Prnova, M. Majekova and M. Stefek, Monatsh. Chem., 149, 921 (2018); https://doi.org/10.1007/s00706-018-2146-6.
X. Wang, T. Zhao, B. Yang, Z. Li, J. Cui, Y. Dai, Q. Qiu, H. Qiang, W. Huang and H. Qian, Bioorg. Med. Chem. Lett., 23, 132 (2015); https://doi.org/10.1016/j.bmc.2014.11.016.
A. Ghafoor and S.A.J. Khan, List of Diseases of Econonomic Plants in Pakistan, Ministry of Food and Agriculture, Islamabad, Pakistan, pp. 26 (1976).
I. Rzewnicki, E. Olszewska and D. Rogowska-Szadkowska, Med. Sci. Monit., 18, RA17 (2012); https://doi.org/10.12659/MSM.882505.
G.L. Gard, H.B. Davis, R.M. Sheets, J.M. Brannfors and W.W. Paudler, Heterocycles, 20, 2029 (1983); https://doi.org/10.3987/R-1983-10-2029.
C.F. Koelsch, J. Am. Chem. Soc., 53, 304 (1931); https://doi.org/10.1021/ja01352a042.
Atta-ur-Rahman, M.I. Choudhary and W.J. Thomsen, Bioassay Techniques for Drug Dtwelopment, Harwood Academic Publishers, The Netherlands, p. 16 (2001).
K.M. Khan, Z.S. Saify, M.Z. Khan, Zia-Ullah, M.I. Choudhary, Attaur-Rahman, S. Perveen, Z.H. Chohan and C.T. Supuran, J. Enzym. Inhib. Med. Chem., 19, 373 (2004); https://doi.org/10.1080/14756360409162453.