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Vol. 30 No. 2 (2018): Vol 30 Issue 2

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Synthesis, Characterization and Antimicrobial Screening of 1,3-Dione with their Metal Complexes

https://doi.org/10.14233/ajchem.2018.21041
Sandeep N. Sampal
Department of Chemistry, Kalikadevi Arts, Commerce and Science College, Shirur (Kasar), Beed-413 249, India
Shailendrasingh V. Thakur
Department of Chemistry, Milliya Arts, Science and Management Science College, Beed-431 122, India
Anjali S. Rajbhoj
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004 India
Suresh T. Gaikwad
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004 India

Corresponding Author(s) : Suresh T. Gaikwad

gaikwadsuresh12@gmail.com

Asian Journal of Chemistry, Vol. 30 No. 2 (2018): Vol 30 Issue 2

Abstract

1-(5-Bromo-2-hydroxyphenyl)-3-(thiophen-2-yl)-propane-1,3-dione and its metal complexes has been synthesized. The functionalized 1,3-dione potentially acts as bidentate ligand and coordinate with the transition metal ions through b-diketo system. The synthesized diketone and their transition metal complexes have been screened for in vitro antibacterial and antifungal activity using Resazurin 96 well plate method. The transition metal complexes showed moderate to excellent antimicrobial activity against all tested bacteria and fungi which constitutes a new group of compounds that can be used as potential metal derived drugs.

Keywords

1,3-Dione Metal complexes Magnetic susceptibility XRD TGA Antimicrobial activity
Sampal, S. N., Thakur, S. V., Rajbhoj, A. S., & Gaikwad, S. T. (2017). Synthesis, Characterization and Antimicrobial Screening of 1,3-Dione with their Metal Complexes. Asian Journal of Chemistry, 30(2), 398–402. https://doi.org/10.14233/ajchem.2018.21041
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