Synthesis and characterization of 3-formyl-1H-2-benzopyran-1-one is reported through convenient three step method. Homophthalic acid and ethyloxalyl chloride were refluxed to afford isocoumarin 3-ethylcarboxylate, which was subsequently heated to reflux with ethanolic hydrazine hydrate to yield isocoumarin-3-hydrazide. The product is treated with ammoniacal solution of metaperiodate to synthesize 3-formyl-1H-2-benzopyran-1-one. All products were characterized by IR, NMR and mass spectral analysis. Physical and spectral data were in close agreement with those, reported in literature.
Hussain, M., Badaruddin Ahmad, H., Aslam Shad, M., Hussain, A., Yousaf, M., Uzair, M., & Shafiq, Z. (2012). Synthesis and Characterization of 3-Formyl-1H-2-benzopyran-1-one. Asian Journal of Chemistry, 24(12), 5473–5475. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9908
