Simultaneous Quantitative Determination of Gentiana scabra by HPLC-MS/MS
Zengxi Guo
Department of Traditional Chinese Medicine, Zhejiang Institute for Food and Drug Control, No 86, Lane 1, Jichang Road, Jianggan Dist. 310004, Hangzhou Zhejiang Province, P.R. China
Yongchi Zeng
Hangzhou Innovation TCM Standarization Research Institute Co. Ltd., No 677, Binkang Road, Binjiang Dist. 310053, Hangzhou Zhejiang Province, P.R. China
Qinwei Huang
Department of Traditional Chinese Medicine, Zhejiang Institute for Food and Drug Control, No 86, Lane 1, Jichang Road, Jianggan Dist. 310004, Hangzhou Zhejiang Province, P.R. China
Xiaqian Cheng
College of Pharmaceutical Science, Zhejiang Chinese Medicinal University, No 548, Bingwen Road, Binjiang Dist. 310053, Hangzhou Zhejiang Province, P.R. China
Weiming Cheng
Department of Traditional Chinese Medicine, Zhejiang Institute for Food and Drug Control, No 86, Lane 1, Jichang Road, Jianggan Dist. 310004, Hangzhou Zhejiang Province, P.R. China
Corresponding Author(s) : Weiming Cheng
weiming_cheng@hotmail.com
Asian Journal of Chemistry,
Vol. 24 No. 11 (2012): Vol 24 Issue 11
An approach for simultaneous quantitative determination of bioactive components in traditional Chinese medicine, using HPLC-MS/MS technique was described in this paper. Gentiana scabra, a well-known traditional Chinese medicine, was studied using the established method as for an application. The column was Kromasil C18 and the gradient mobile phase was optimized for a better resolution. As a result, the linearities and recoveries of the 6 components were suitable and good for the detection. This work could provide a simple, rapid and relatively comprehensive quality control method for the clinical safety of G. scabra.
Guo, Z., Zeng, Y., Huang, Q., Cheng, X., & Cheng, W. (2012). Simultaneous Quantitative Determination of Gentiana scabra by HPLC-MS/MS. Asian Journal of Chemistry, 24(11), 5365–5367. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9869
