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Vol. 24 No. 11 (2012): Vol 24 Issue 11

Amino Acid-Catalyzed Synthesis of Triarylimidazoles-A New Green Protocol

Fatima Ijaz
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Shazia Noreen
Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Muhammad Naeem Khan
Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Sadia Naureen
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Misbahul Ain Khan
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan ; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Munawar Ali Munawar
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Alice Maria Rolim Bernardino
Instituto de Química, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil

Corresponding Author(s) : Muhammad Naeem Khan

changwani_1@yahoo.com

Asian Journal of Chemistry, Vol. 24 No. 11 (2012): Vol 24 Issue 11

Abstract

A green and efficient solventless method using a variety of amino acids as catalysts at 100 ºC for a few minutes, were used for the synthesis of 2,4,5-triaryl-1H-imidazoles. Another mild method for the synthesis of triarylimidazoles using amino acid catalysts in ethanol solvent is also described. The yields are excellent in all cases.

Keywords

Triarylimidazoles Benzil Benzoin Glycine Leucine Phenyl alanine MCRs
Ijaz, F., Noreen, S., Naeem Khan, M., Naureen, S., Ain Khan, M., Ali Munawar, M., & Maria Rolim Bernardino, A. (2012). Amino Acid-Catalyzed Synthesis of Triarylimidazoles-A New Green Protocol. Asian Journal of Chemistry, 24(11), 5114–5116. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9860
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