Copyright (c) 2016 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Evaluation of DPPH Radical Scavenging Activity of 2-(Furan-2'-yl)-3-hydroxy-4H-chromen-4-one and Their Derivatives
Corresponding Author(s) : Manisha Bansal
Asian Journal of Chemistry,
Vol. 28 No. 9 (2016): Vol 28 Issue 9
Abstract
The 2-(furan-2'-yl)-3-hydroxy-4H-chromen-4-one and their substituted derivatives with electron donating and electron withdrawing groups have been synthesized. Free radical scavenging activity has been studied using 2,2'-diphenyl-1-picrylhydrazine (DPPH). The kinetic studies and co-relation of excited state intramolecular proton transfer (ESIPT) with electron donating and electron withdrawing group explains the effect of these groups on percentage scavenging activity.
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
- E. Middleton, Trends Pharmacol. Sci., 5, 335 (1984).
- J.B. Harborne, The flavonoids: Advances in research since 1980, Lon-don: Chapman & Hall: (1988).
- J. Robak and R.J. Gryglewski, Biochem. Pharmacol., 37, 837 (1988).
- W. Bors and M. Saran, Free Radic. Res. Commun., 2, 289 (1987).
- W. Bors, W. Heller, C. Michel and M. Saran, Methods Enzymol., 186, 343 (1990).
- J. Sun, Y. Chen, M. Li and Z. Ge, Free Radic. Biol. Med., 24, 586 (1998).
- A. El Abbouyi, S. Khlifi, Y. El Hachimi, A. Khalil, N. Es-Safi, A. Belahyan and R. Tellal, Indian J. Pharmacol., 38, 276 (2006).
- I. Gulcin, H.A. Alici and M. Cesur, Pharmacol. Bull., 53, 281 (2005).
- N. Cotelle, J.L. Bernier, J.P. Henichart, J.P. Catteau, E. Gaydou and J.C. Wallet, Free Radic. Biol. Med. (Paris), 13, 211 (1992).
- M. Matgorzata, Pol. J. Food. Nutr. Sci., 58, 407 (2008).
- H. Venkatachalam, Y. Nayak and B.S. Jayashree, Int. J. Chemical Eng. Application, 3, 216 (2012).
- M. Bansal and R. Kaur, J. Chem. Sci., 127, 405 (2015).
- A.S. Klymchenko and A.P. Demchenko, New J. Chem., 28, 687 (2004).
- A.S. Klymchenko, V.G. Pivovarenko, T. Ozturk and A.P. Demchenko, New J. Chem., 27, 1336 (2003).
- A.S. Klymchenko and A.P. Demchenko, J. Am. Chem. Soc., 124, 12372 (2002).
References
E. Middleton, Trends Pharmacol. Sci., 5, 335 (1984).
J.B. Harborne, The flavonoids: Advances in research since 1980, Lon-don: Chapman & Hall: (1988).
J. Robak and R.J. Gryglewski, Biochem. Pharmacol., 37, 837 (1988).
W. Bors and M. Saran, Free Radic. Res. Commun., 2, 289 (1987).
W. Bors, W. Heller, C. Michel and M. Saran, Methods Enzymol., 186, 343 (1990).
J. Sun, Y. Chen, M. Li and Z. Ge, Free Radic. Biol. Med., 24, 586 (1998).
A. El Abbouyi, S. Khlifi, Y. El Hachimi, A. Khalil, N. Es-Safi, A. Belahyan and R. Tellal, Indian J. Pharmacol., 38, 276 (2006).
I. Gulcin, H.A. Alici and M. Cesur, Pharmacol. Bull., 53, 281 (2005).
N. Cotelle, J.L. Bernier, J.P. Henichart, J.P. Catteau, E. Gaydou and J.C. Wallet, Free Radic. Biol. Med. (Paris), 13, 211 (1992).
M. Matgorzata, Pol. J. Food. Nutr. Sci., 58, 407 (2008).
H. Venkatachalam, Y. Nayak and B.S. Jayashree, Int. J. Chemical Eng. Application, 3, 216 (2012).
M. Bansal and R. Kaur, J. Chem. Sci., 127, 405 (2015).
A.S. Klymchenko and A.P. Demchenko, New J. Chem., 28, 687 (2004).
A.S. Klymchenko, V.G. Pivovarenko, T. Ozturk and A.P. Demchenko, New J. Chem., 27, 1336 (2003).
A.S. Klymchenko and A.P. Demchenko, J. Am. Chem. Soc., 124, 12372 (2002).