Antibacterial and Antifungal Properties of Flavonoid Compounds from Osmunda japonica thumb

Abstract

Osmunda japonica thumb, widely used for human consumption, is also Chinese traditional medicine. In the study, we showed that the flavonoid compounds of Osmunda japonica thumb exert a potent antibacterial and antifungal activity. Results showed that the flavonoid compounds can remarkably inhibit the proliferation of P. vulgaris, P. aeruginosa, E. coli, B. subtilis, A. niger and A. flavus and its minimum inhibitory concentrations (MICs) was 50 μg/mL (E. coli and B. subtilis) and 100 μg/mL (P. vulgaris, P. aeruginosa, A. niger and A. flavus), respectively. The results provide promising baseline information for the potential use of the extract and flavonoids from this plant as antimicrobial agents to help control some microbial diseases.