The pyrazolo pyrimidinone was prepared by treatment of 4-amino-5-pyrazole carboxamide with 2-ethoxy benzoic acid and the product characterized using NMR, high resolution mass spectrometry and X-ray crystallography. In the crystal, the hydrogen bonds and intermolecular interactions join the bridge between O26 of one molecule and C10-H10A of another. The molecule (C22H30N6O4S) crystallized in the monoclinic P2(1)/c space group. Unit cell parameters for 5-(2-ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl)-1-methyl-3-propyl-1,6-dihydro-pyrazolo(4,3-d)pyrimidin-7-one: a = 17.2898(4), b = 6.9755(3), c = 8.0757(2)Å, b = 100.0710(10) and Z = 4.
Park, H.-M., Chang, B.-J., Jin, H., & Kim, J.-H. (2012). Synthesis and Structural Characterization of the Aminopyrazole Derived Pyrimidinone. Asian Journal of Chemistry, 24(9), 4163–4165. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9573
