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Vol. 24 No. 9 (2012): Vol 24 Issue 9

Preparation and Antibacterial Activity of Ag/Chitosan Complex

Benhong Yang
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China
Meng Li
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China
Yun Wu
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China
Chonghai Deng
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China
Xuelian Yu
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China
Hui Zhang
Department of Chemistry and Materials Engineering, Hefei University, Hefei 230022, P.R. China

Corresponding Author(s) : Benhong Yang

yangbh@hfuu.edu.cn

Asian Journal of Chemistry, Vol. 24 No. 9 (2012): Vol 24 Issue 9

Abstract

While retaining the original activity of chitosan (CTS), water-soluble carboxymethylated chitosan (CM-CTS) was first synthesized via the carboxymethylation of chitosan with chloroacetic acid and then complexed with silver ions to form stronger antimicrobial agent (Ag/CM-CTS). FTIR was employed to characterize and confirm the structures of each product. Antimicrobial tests show that Ag/CM-CTS has much higher antimicrobial activity than both CTS and CM-CTS against ether E. coli or B. subtilis. The minimum inhibitory concentrations of Ag/CM-CTS against E. coli and B. subtilis are 0.1 and 0.2 mg/mL, respectively.

Keywords

Antibacterial agent Chitosan Silver ion Carboxymethylation
(1)
Yang, B.; Li, M.; Wu, Y.; Deng, C.; Yu, X.; Zhang, H. Preparation and Antibacterial Activity of Ag Chitosan Complex. ajc 2012, 24, 4019-4021.
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