L-Cysteine-capped CdTe Quantum Dots Based Fluorescence Quenching Method for Determination of Chloroamphenicol
Yongqiang Mao
School of Chemical Engineering and Technology, Tianjin University, Tianjin, P.R. China ; College of Science, Liaoning Technical University, Fuxin, P.R. China
Na Li
College of Science, Liaoning Technical University, Fuxin, P.R. China
Ye Han
School of Chemical Engineering and Technology, Tianjin University, Tianjin, P.R. China
Baoan Ning
Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Institute of Health and Environmental Medicine, Tianjin, P.R. China
Zhixian Gao
Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Institute of Health and Environmental Medicine, Tianjin, P.R. China
Zhijiang Zhou
School of Chemical Engineering and Technology, Tianjin University, Tianjin, P.R. China
Corresponding Author(s) : Zhijiang Zhou
zzjtju@126.com; gaozhx@126.com
Asian Journal of Chemistry,
Vol. 24 No. 8 (2012): Vol 24 Issue 8
L-Cysteine-capped CdTe quantum dots (QDs) with a narrow, symmetric emission spectrum was synthesized in aqueous medium. Based on the fluorescence quenching of CdTe quantum dots, a simple, rapid and sensitive method was developed for the quantitative determination of chloroamphenicol. Under optimum conditions, the calibration plot of the relative fluorescence intensity with the concentration of chloroamphenicol was linear in the range from 5 to 40 μg mL-1 with the correlation coefficient of 0.9963. The limit of detection was 50 ng mL-1. The content of chloroamphenicol in pharmaceutical tablet were determined by the proposed method and the results agreed with the claimed value. In addition, the possible fluorescence quenching mechanism was also discussed.
Mao, Y., Li, N., Han, Y., Ning, B., Gao, Z., & Zhou, Z. (2012). L-Cysteine-capped CdTe Quantum Dots Based Fluorescence Quenching Method for Determination of Chloroamphenicol. Asian Journal of Chemistry, 24(8), 3715–3718. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9432
