Spectrophotometric Determination of Centrophenoxine Hydrochloride with Colour Reaction of Rose Bengal
Wei-Xing Ma
School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, Jiangsu Province, P.R. China ; Jiangsu-Marine Resources Development Research Institute, Lianyungang 222005, Jiangsu Province, P.R. China ; Key Lab of Applied Chemistry, Huaihai Institute of Technology, Lianyungang 222005, Jiangsu Province, P.R. China
Yan Zhou
School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, Jiangsu Province, P.R. China
Qiao Ling Wang
School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, Jiangsu Province, P.R. China
Zheng Zhang
School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, Jiangsu Province, P.R. China
Corresponding Author(s) : Wei-Xing Ma
weixingma650528@163.com; weixingma650528@126.com
Asian Journal of Chemistry,
Vol. 24 No. 8 (2012): Vol 24 Issue 8
A new spectrophotometric method for determination of centrophenoxine hydrochloride was proposed based on the colour reaction of centrophenoxine hydrochloride with rose bengal to form ion association complex in the Clark-Lubs buffer media with pH 2.6, whose maximum wavelength was at 568 nm with the apparent molar absorptivity of complex was 5.589 × 103 L mol-1 cm-1, Beer law was obeyed in the range of 2-21 mg L-1 for centrophenoxine hydrochloride. The proposed method was stable, accurate, sensitive and rapid and has been applied for the determination of centrophenoxine hydrochloride with satisfactory results.
Ma, W.-X., Zhou, Y., Ling Wang, Q., & Zhang, Z. (2012). Spectrophotometric Determination of Centrophenoxine Hydrochloride with Colour Reaction of Rose Bengal. Asian Journal of Chemistry, 24(8), 3483–3486. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/9412