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Vol. 24 No. 8 (2012): Vol 24 Issue 8

Synthesis of Antibiotic Linezolid Analogues

Pingili Krishna Reddy
Symed Research Centre, Plot No. 89/A, Phase-I, Shapoornagar, IDA Jeedi Metla, Hyderabad500 055, India ; Center for Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad-500 085, India
K. Mukkanti
Center for Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad-500 085, India
Dodda Mohan Rao
Symed Research Centre, Plot No. 89/A, Phase-I, Shapoornagar, IDA Jeedi Metla, Hyderabad500 055, India

Corresponding Author(s) : Dodda Mohan Rao

kreddysymed@yahoo.com

Asian Journal of Chemistry, Vol. 24 No. 8 (2012): Vol 24 Issue 8

Abstract

Several new compounds of oxazolidinone class were designed, synthesized and their analogs were evaluated for antibacterial activity against Staphylococcus aureus, Staphylococcus citreus, Proteus vulgaris, Salmonella typhimurium and Klabsiella phenumoniae. The structures of all the compounds were confirmed by IR, 1H NMR, 13C NMR and mass spectral data.

Keywords

Oxazolidinone Epichlorohydrin Antibacterial Linezolid
(1)
Krishna Reddy, P.; Mukkanti, K.; Mohan Rao, D. Synthesis of Antibiotic Linezolid Analogues. ajc 2012, 24, 3479-3482.
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