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Vol. 28 No. 9 (2016): Vol 28 Issue 9

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Synthesis and Antibacterial Activity of Substituted Quinoline Derivatives

https://doi.org/10.14233/ajchem.2016.19393
S. Ravindra
Centre for Chemical Sciences and Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, India
Alka Rani
Department of Chemistry, Hindu College, Moradabad-244 001, India

Corresponding Author(s) : Alka Rani

alka.c@yahoo.com

Asian Journal of Chemistry, Vol. 28 No. 9 (2016): Vol 28 Issue 9

Abstract

An efficient and convenient method is reported for the synthesis of various substituted quinolines through the condensation of o-amino aryl carbonyls with ketones containing an active methylene group in the presence of CuSO4·5H2O as catalyst at room temperature to yeild substituted quinolines (3a-l). All the synthesized compounds were fully characterized and screened for their antibacterial activities.

Keywords

Substituted quinolines Antibacterial activity o-Aminoarylketone
Ravindra, S., & Rani, A. (2016). Synthesis and Antibacterial Activity of Substituted Quinoline Derivatives. Asian Journal of Chemistry, 28(9), 1891–1894. https://doi.org/10.14233/ajchem.2016.19393
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