Synthesis of Fluorine-Containing a-Acyloxycarboxamide Derivatives from Indane-1,2,3-trione, Isocyanides and 4-Fluorobenzoic Acid
Corresponding Author(s) : Ali Reza Kazemizadeh
alirezakazemizadeh@yahoo.com
Asian Journal of Chemistry,
Vol. 24 No. 8 (2012): Vol 24 Issue 8
Abstract
Passerini reaction of indane-1,2,3-trione, isocyanides and 4-fluorobenzoic acid proceed at room temperature and the related fluorine-containing a-acyloxycarboxamide derivatives are synthesized in quantitative yields. The reactions are one-pot, single spot and the products were obtained without any purification.
Keywords
Fluorine-containing a-acyloxycarboxamide
Multicomponent reaction
Passerini reaction
Indane-1,2,3-trione
Isocyanide
4-Fluorobenzoic acid
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Reza Kazemizadeh, A.; Ramazani, A. Synthesis of Fluorine-Containing a-Acyloxycarboxamide Derivatives from Indane-1,2,3-Trione, Isocyanides and 4-Fluorobenzoic Acid. ajc 2012, 24, 3383-3385.
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