One-Pot Synthesis of Quinoxalines Starting from Aldehydes Under Metal-Free Conditions

Zhong-Yuan Hu; Ding Du; Wei-Fang Tang; Tao Lu

Issue

Vol. 24 No. 5 (2012): Vol 24 Issue 5

Issue Published : December 30, 2011

One-Pot Synthesis of Quinoxalines Starting from Aldehydes Under Metal-Free Conditions

Zhong-Yuan Hu

State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, P.R. China

Ding Du

State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, P.R. China

Wei-Fang Tang

State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, P.R. China

Tao Lu

State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, P.R. China

Corresponding Author(s) : Ding Du

dd820322@126.com; lut163@163.com

Asian Journal of Chemistry, Vol. 24 No. 5 (2012): Vol 24 Issue 5
Article Published : January 3, 2012

Abstract

An efficient and convenient synthesis of quinoxalines from easily available aldehydes was performed as a one-pot procedure in good to excellent yields under metal-free conditions, via sequential benzoin condensation, aerobic formation of benzils and condensation of the latter with 1,2-diaminobenzenes.

Keywords

Quinoxalines Aldehydes One-pot synthesis N-Heterocyclic carbene

Hu, Z.-Y., Du, D., Tang, W.-F., & Lu, T. (2012). One-Pot Synthesis of Quinoxalines Starting from Aldehydes Under Metal-Free Conditions. Asian Journal of Chemistry, 24(5), 2262–2264. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/8995

Issue

Vol. 24 No. 5 (2012): Vol 24 Issue 5

One-Pot Synthesis of Quinoxalines Starting from Aldehydes Under Metal-Free Conditions

Corresponding Author(s) : Ding Du

Abstract

Keywords

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