Cosmetic Application of Phenolic Cream from Mulberry Bark Extract

Abstract

The aim of this study is to determine the effects of newly formulated O/W emulsion (cream) of ethanolic mulberry extract versus its vehicle (base) as control on skin melanin, skin erythema and skin moisture content. Concentrated 4 % mulberry extract was entrapped in the inner aqueous phase of O/W emulsion. The newly formulated base and formulation were applied to the cheeks of undiseased human volunteers for a period of 8 weeks. Melanin, erythema and skin moisture were monitored every week and analyzed by Mexameter and Corneometer. Statistically the results of both base and formulation were compared by using ANOVA and Paired t-test. The base showed insignificant (p > 0.05) effects while the formulation showed statistically significant (p £ 0.05) decrease in melanin content. Both the base and formulation showed insignificant (p > 0.05) effects on skin moisture content. Skin erythema was significantly (p £ 0.05) reduced by the formulation. This formulation of cream containing 4 % concentrated extract of mulberry can be used for skin whitening as it decreased skin melanin content. Furthermore, the decrease in erythema demonstrated that the cream will be safe to use and will not cause any irritation. The formulation is suggested not to be used in cold season as it causes dryness.