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Synthesis of Some Pyridazine Based Pyrazolines
Corresponding Author(s) : Samina Aslam
Asian Journal of Chemistry,
Vol. 28 No. 7 (2016): Vol 28 Issue 7
Abstract
3-Chloro-6-hydrazinyl pyridazine reacts with chalcones to give 1,3,5-trisubstituted pyrazolines. Some of these display reasonable antibacterial activity.
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- R.H. Wiley, in eds.: L.C. Behr, R. Fusco and C.H. Jarboe, Pyrazoles, Pyrazolines, Pyrazolidines, Indazoles and Condensed Rings, Interscience Publishers, New York (1967).
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- J.H.M. Lange, H.K.A.C. Coolen, H.H. van Stuivenberg, J.A.R. Dijksman, A.H.J. Herremans, E. Ronken, H.G. Keizer, K. Tipker, A.C. McCreary, W. Veerman, H.C. Wals, B. Stork, P.C. Verveer, A.P. den Hartog, N.M.J. de Jong, T.J.P. Adolfs, J. Hoogendoorn and C.G. Kruse, J. Med. Chem., 47, 627 (2004); doi:10.1021/jm031019q.
- A.Q. Ather, F. Chaudhry and M.N. Khan, Asian J. Chem., 25, 7743 (2013); doi:10.14233/ajchem.2013.14590.
- C. Limban, M.-C.B. Chifiriuc, A.-V. Missir, I.C. Chiriţă and C. Bleotu, Molecules, 13, 567 (2008); doi:10.3390/molecules13030567.
- S. Syam, S.I. Abdelwahab, M.A. Al-Mamary and S. Mohan, Molecules, 17, 6179 (2012); doi:10.3390/molecules17066179.
References
R.H. Wiley, in eds.: L.C. Behr, R. Fusco and C.H. Jarboe, Pyrazoles, Pyrazolines, Pyrazolidines, Indazoles and Condensed Rings, Interscience Publishers, New York (1967).
M. Yusuf and P. Jain, Arabian J. Chem., 7, 553 (2014); doi:10.1016/j.arabjc.2011.09.013.
E. Palaska, M. Aytemir, I.T. Uzbay and D. Erol, Eur. J. Med. Chem., 36, 539 (2001); doi:10.1016/S0223-5234(01)01243-0.
D. Nauduri and G.B. Reddy, Chem. Pharm. Bull. (Tokyo), 46, 1254 (1998); doi:10.1248/cpb.46.1254.
R.H. Udupi, A.S. Kushnoor and A.R. Bhat, Indian J. Heterocycl. Chem., 8, 63 (1998).
J.H.M. Lange, H.K.A.C. Coolen, H.H. van Stuivenberg, J.A.R. Dijksman, A.H.J. Herremans, E. Ronken, H.G. Keizer, K. Tipker, A.C. McCreary, W. Veerman, H.C. Wals, B. Stork, P.C. Verveer, A.P. den Hartog, N.M.J. de Jong, T.J.P. Adolfs, J. Hoogendoorn and C.G. Kruse, J. Med. Chem., 47, 627 (2004); doi:10.1021/jm031019q.
A.Q. Ather, F. Chaudhry and M.N. Khan, Asian J. Chem., 25, 7743 (2013); doi:10.14233/ajchem.2013.14590.
C. Limban, M.-C.B. Chifiriuc, A.-V. Missir, I.C. Chiriţă and C. Bleotu, Molecules, 13, 567 (2008); doi:10.3390/molecules13030567.
S. Syam, S.I. Abdelwahab, M.A. Al-Mamary and S. Mohan, Molecules, 17, 6179 (2012); doi:10.3390/molecules17066179.