An Improvement in Synthesis of 6-Ethyl-5-fluoro-pyrimidin-4-ol

Wenhua Ou; Feng Liu; Xianhua Pan

Issue

Vol. 24 No. 3 (2012): Vol 24 Issue 3

Issue Published : 2 November 2011

An Improvement in Synthesis of 6-Ethyl-5-fluoro-pyrimidin-4-ol

Wenhua Ou

School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, P.R. China

Feng Liu

School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, P.R. China

Xianhua Pan

School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, P.R. China

Corresponding Author(s) : Wenhua Ou

ouwenhua72@hotmail.com; 123owh@163.com

Asian Journal of Chemistry, Vol. 24 No. 3 (2012): Vol 24 Issue 3
Article Published : 13 December 2011

Abstract

An effective and simple method for the preparation of 6-ethyl-5-fluoropyrimidin-4-ol is reported. It used formamide instead of formamidine acetate. It is new cyclization for synthesis of 6-ethyl- 5-fluoropyrimidin-4-ol.

Keywords

Voriconazole 6-Ethyl-5-fluoropyrimidin-4-ol Formamide

(1)

Ou, W.; Liu, F.; Pan, X. An Improvement in Synthesis of 6-Ethyl-5-Fluoro-Pyrimidin-4-Ol. ajc 2011, 24, 1409-1410.

Issue

Vol. 24 No. 3 (2012): Vol 24 Issue 3

An Improvement in Synthesis of 6-Ethyl-5-fluoro-pyrimidin-4-ol

Corresponding Author(s) : Wenhua Ou

Abstract

Keywords

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