Synthesis, Characterization, Antimicrobial Activity and DNA Studies of Novel Schiff's Base Complexes of Some Transition Metal Ions

Abstract

A bidentate chelating Schiff base (L) and its complexes with Fe(II), Co(II), Ni(II), Cu(II) and Ru(III) metal ions have been synthesized and characterized by elemental analysis, IR, ¹H NMR and ¹³C NMR spectral studies. The cyclic voltammetric studies were carried out to understand the redox characteristics of some of these complexes. EPR spectral studies and calculation of LFSE, 10Dq, b and μ_eff have been carried out to prove the existence of covalency in the M-L bond. Interactions of these complexes with calf thymus DNA were investigated by UV-visible absorption spectroscopy and gel electrophoresis. Antimicrobial activity of these compounds have also been studied.