Synthesis and Crystal Structure of (Z)-3-Benzyl-5- [4-(benzyloxy)-3-methoxybenzylidene]thiazolidine-2,4-dione

Abstract

The synthesis and crystal structure of the (Z)-3-benzyl-5-(4-(benzyloxy)-3- methoxybenzylidene)thiazolidine-2,4-dione has been determined by single crystal X-ray diffraction method. The crystal belongs to triclinic, space group P1, with a = 9.098(4), b = 10585(5), c = 11.609(5)Å, a = 80.549(6), b = 88.159(6), g = 71.587(4)°, V = 1046.2(8)ų, Z = 2, Dx = 1.370 Mg/m³, l(MoK_a) = 0.71073, F(000) = 452, μ(MoK_a) = 0.188 mm^-1, R = 0.0815 and wR = 0.2507 for 2038 reflections with I > 2s(I). The C(6)-C(7) bond (1.506 Å) confirm the delocalization of the p electrons between thiazolidine-2,4-dione ring and benzene ring in the title compound, but the thiazolidine-2,4-dione ring and benzene C(7)-C(12) planes are not in the same plane and make a dihedral angle of 16.69(0.20)º with each other.