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Vol. 25 No. 17 (2013): Vol 25 Issue 17

Copyright (c) 2013 AJC

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Triterpenoides from the Leaves of Ilex pubescens and their Potential Xanthine Oxidase Inhibitory Activity

https://doi.org/10.14233/ajchem.2013.15024
Zhong-Liu Zhou
Chemistry Science and Technology School, Zhanjiang Normal University, Zhanjiang, P.R. China
Zong-Cai Feng
Development Center for New Materials Engineering & Technology in Universities of Guangdong, Zhanjiang Normal University, Zhanjiang, P.R. China
Jing-Min Xia
Chemistry Science and Technology School, Zhanjiang Normal University, Zhanjiang, P.R. China

Corresponding Author(s) : Zhong-Liu Zhou

zlzhou@hotmail.com

Asian Journal of Chemistry, Vol. 25 No. 17 (2013): Vol 25 Issue 17

Abstract

A new triterpene saponin, ilexsaponin B (1), along with three known triterpenoides, 2a, 3b, 19a, 23-tetrahydroxy oleanolic acid (2), ilexgenin A (3) and ilexolide A (4) were isolated from the leaves of Ilex pubescens. Their chemical structures were elucidated on the basis of UV, IR, MS, NMR spectroscopic analyses coupled with chemical degradation. In addition, the xanthine oxidase inhibitory activity of the isolated compounds was reported. Compound 1 exhibited moderate xanthine oxidase inhibitory activity in the test with an IC50 value of 26.01 μmol/L.

Keywords

Ilex pubescens Triterpenoide Ilexsaponin B Xanthine oxidase
Zhou, Z.-L., Feng, Z.-C., & Xia, J.-M. (2013). Triterpenoides from the Leaves of Ilex pubescens and their Potential Xanthine Oxidase Inhibitory Activity. Asian Journal of Chemistry, 25(17), 9457–9459. https://doi.org/10.14233/ajchem.2013.15024
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