Antiviral Fluorenone Derivatives from Arundina gramnifolia
Corresponding Author(s) : Xue-Mei Gao
gao_xuemei@hotmail.com
Asian Journal of Chemistry,
Vol. 25 No. 17 (2013): Vol 25 Issue 17 page 9514-9516
Abstract
A new fluorenone derivative, gramniphenol H (1), together with four known fluorenone derivatives (2-5) were isolated from the whole plant of Arundina gramnifolia. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compound 1 was tested for its cytotoxicity against five human tumor cell lines and it shows modest cytotoxicity against PC3 and SHSY5Y cell with IC50 values of 6.18 and 4.25 μM, respectively.
Keywords
Arundina gramnifolia
Fluorenone
Structural elucidation
Cytotoxicity
Niu, D.-Y., Han, J.-M., Kong, W.-S., Cui, Z.-W., Hu, Q.-F., & Gao, X.-M. (2013). Antiviral Fluorenone Derivatives from Arundina gramnifolia. Asian Journal of Chemistry, 25(17), 9514-9516. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/8538
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