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Vol. 25 No. 17 (2013): Vol 25 Issue 17

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Submitted
Sep 30, 2020
Published
Nov 11, 2013

Antiviral Fluorenone Derivatives from Arundina gramnifolia

De-Yun Niu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Jing-Mei Han
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Wei-Song Kong
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Zhu-Wen Cui
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Qiu-Fen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Xue-Mei Gao
gao_xuemei@hotmail.com
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China

Corresponding Author(s) : Xue-Mei Gao

gao_xuemei@hotmail.com

Asian Journal of Chemistry, Vol. 25 No. 17 (2013): Vol 25 Issue 17 page 9514-9516

Abstract

A new fluorenone derivative, gramniphenol H (1), together with four known fluorenone derivatives (2-5) were isolated from the whole plant of Arundina gramnifolia. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compound 1 was tested for its cytotoxicity against five human tumor cell lines and it shows modest cytotoxicity against PC3 and SHSY5Y cell with IC50 values of 6.18 and 4.25 μM, respectively.

Keywords

Arundina gramnifolia Fluorenone Structural elucidation Cytotoxicity
Niu, D.-Y., Han, J.-M., Kong, W.-S., Cui, Z.-W., Hu, Q.-F., & Gao, X.-M. (2013). Antiviral Fluorenone Derivatives from Arundina gramnifolia. Asian Journal of Chemistry, 25(17), 9514-9516. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/8538
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