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Phytochemical Evaluation and Screening of in vitro Antioxidant Potentiality of Extracts of Ixora chinensis Lam Leaves
Corresponding Author(s) : Sunitha Dontha
Asian Journal of Chemistry,
Vol. 28 No. 7 (2016): Vol 28 Issue 7
Abstract
From Ixora chinensis Lam leaves, we obtained petroleum ether (60-80°), ethyl acetate and n-butanol extracts by soxhilation. The crude extracts obtained were tested for chemical identification of groups that may be the basis of the expected therapeutic effects. The preliminary phytochemical investigation led to the presence of flavonoids, triterpenoids, sterols, glycosides, carbohydrates, etc. in vitro antioxidant activity was evaluated using DPPH free radical scavenging assay, superoxide radical scavenging and nitric oxide methods and % inhibitions were calculated for all the methods.
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- X.-Y. Su, Z.-Y. Wang and J.-R. Liu, Food Chem., 117, 681 (2009); doi:10.1016/j.foodchem.2009.04.076.
- O. Kaisoon, S. Siriamornpun, N. Weerapreeyakul and N. Meeso, J. Funct. Foods, 3, 88 (2011); doi:10.1016/j.jff.2011.03.002.
- K.R. Kirtikar and B.D. Basu, Indian Medicinal Plants, Oriental Enterprises: Dehradun, Uttaranchal, India, edn 2 (2001).
- S. Bose, S. Maji and P. Chakraboty, Int. J. Biomed. Pharm. Sci., 2, 84 (2008).
- R.S. Moni, A.M. Ashraful, A. Raushanara and J. Rumana, Bangladesh J. Pharmacol., 3, 90 (2009).
- S. Bose, S. Maji and P. Chakraboty, J. Pharm. Sci. Technol., 2, 72 (2013).
- S. Bose, S. Maji and P. Chakraboty, J. Adv. Pharm. Educ. Res., 2, 90 (2011).
- D.M.M. Faten and I.Z. Zedan, Bull. Pharm. Sci., 26, 91 (2003).
- C.R. Metcalfe and L. Chalk, Anatomy of Dicotyledones, The Clarendon Press, Oxford (1970).
- F. Aktar, K.A. Md, K.A.N.M. Hamidul, C.M. Hasan and M.A. Rashid, Dhaka Univ. J. Pharm. Sci., 8, 161 (2009).
- M.S. Baliga and P.J. Kurian, Chin. J. Integr. Med., 18, 72 (2012); doi:10.1007/s11655-011-0881-3.
- U.O. Gloria and U.N. Gibson, Int. J. Acad. Res., 3, 381 (2011).
- I. Ambreen, V. Muhammad Ali, S. Shumaila, S.K. Ahmed, T.A. Syed and F. Shaheen, Rec. Nat. Prod., 7, 302 (2013).
- D.T. Plummer, An Introduction to Practical Biochemistry, Tata McGraw-Hill Education, edn 3 (1988).
- G.E. Trease and W.C. Evans, Pharmacognosy, Saunders Publishers, London, edn 15 (2002).
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- P.M. Rajesh and P.J. Natvar, J. Advan. Pharm. Educ. Res., 1, 52 (2011).
- I. Mohammad, I. Mohammad, I. Zafar, H. Javid, H. Hidayat, M. Ahmed and E. Asma, Rec. Nat. Prod., 3, 193 (2009).
- M.S. Hasan, M.I. Ahmed, S. Mondal, S.J. Uddin, M.M. Masud, S.K. Sadhu and M. Ishibashi, Orient. Pharm. Exp. Med., 6, 355 (2006).
- F. Liu, V.E.C. Ooi and S.T. Chang, Life Sci., 60, 763 (1997); doi:10.1016/S0024-3205(97)00004-0.
- N. Sreejayan and M.N.A. Rao, J. Pharm. Pharmacol., 49, 105 (1997); doi:10.1111/j.2042-7158.1997.tb06761.x.
- R. Govindarajan, S. Rastogi, M. Vijayakumar, A. Shirwaikar, A.K.S. Rawat, S. Mehrotra and P. Pushpangadan, Biol. Pharm. Bull., 26, 1424 (2003); doi:10.1248/bpb.26.1424.
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References
X.-Y. Su, Z.-Y. Wang and J.-R. Liu, Food Chem., 117, 681 (2009); doi:10.1016/j.foodchem.2009.04.076.
O. Kaisoon, S. Siriamornpun, N. Weerapreeyakul and N. Meeso, J. Funct. Foods, 3, 88 (2011); doi:10.1016/j.jff.2011.03.002.
K.R. Kirtikar and B.D. Basu, Indian Medicinal Plants, Oriental Enterprises: Dehradun, Uttaranchal, India, edn 2 (2001).
S. Bose, S. Maji and P. Chakraboty, Int. J. Biomed. Pharm. Sci., 2, 84 (2008).
R.S. Moni, A.M. Ashraful, A. Raushanara and J. Rumana, Bangladesh J. Pharmacol., 3, 90 (2009).
S. Bose, S. Maji and P. Chakraboty, J. Pharm. Sci. Technol., 2, 72 (2013).
S. Bose, S. Maji and P. Chakraboty, J. Adv. Pharm. Educ. Res., 2, 90 (2011).
D.M.M. Faten and I.Z. Zedan, Bull. Pharm. Sci., 26, 91 (2003).
C.R. Metcalfe and L. Chalk, Anatomy of Dicotyledones, The Clarendon Press, Oxford (1970).
F. Aktar, K.A. Md, K.A.N.M. Hamidul, C.M. Hasan and M.A. Rashid, Dhaka Univ. J. Pharm. Sci., 8, 161 (2009).
M.S. Baliga and P.J. Kurian, Chin. J. Integr. Med., 18, 72 (2012); doi:10.1007/s11655-011-0881-3.
U.O. Gloria and U.N. Gibson, Int. J. Acad. Res., 3, 381 (2011).
I. Ambreen, V. Muhammad Ali, S. Shumaila, S.K. Ahmed, T.A. Syed and F. Shaheen, Rec. Nat. Prod., 7, 302 (2013).
D.T. Plummer, An Introduction to Practical Biochemistry, Tata McGraw-Hill Education, edn 3 (1988).
G.E. Trease and W.C. Evans, Pharmacognosy, Saunders Publishers, London, edn 15 (2002).
E.A. Sofowora, Screening Plants for Bioactive Agents. In: Medicinal Plants and Traditional Medicinal in Africa, John Wiley & Sons, London, edn 2 (1993).
P.M. Rajesh and P.J. Natvar, J. Advan. Pharm. Educ. Res., 1, 52 (2011).
I. Mohammad, I. Mohammad, I. Zafar, H. Javid, H. Hidayat, M. Ahmed and E. Asma, Rec. Nat. Prod., 3, 193 (2009).
M.S. Hasan, M.I. Ahmed, S. Mondal, S.J. Uddin, M.M. Masud, S.K. Sadhu and M. Ishibashi, Orient. Pharm. Exp. Med., 6, 355 (2006).
F. Liu, V.E.C. Ooi and S.T. Chang, Life Sci., 60, 763 (1997); doi:10.1016/S0024-3205(97)00004-0.
N. Sreejayan and M.N.A. Rao, J. Pharm. Pharmacol., 49, 105 (1997); doi:10.1111/j.2042-7158.1997.tb06761.x.
R. Govindarajan, S. Rastogi, M. Vijayakumar, A. Shirwaikar, A.K.S. Rawat, S. Mehrotra and P. Pushpangadan, Biol. Pharm. Bull., 26, 1424 (2003); doi:10.1248/bpb.26.1424.
F. Conforti, M. Marrelli, C. Carmela, F. Menichini, P. Valentina, D. Uzunov, G.A. Statti, P. Duez and F. Menichini, Food Chem., 129, 1413 (2011); doi:10.1016/j.foodchem.2011.05.085.