Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Yin-Ke Li
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China ; Collge of Resource and Environment, Yuxi Normal University, Yuxi 653100, P.R. China
Xian-Xue Wu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China ; Collge of Resource and Environment, Yuxi Normal University, Yuxi 653100, P.R. China
Yun-Dong Shi
Collge of Resource and Environment, Yuxi Normal University, Yuxi 653100, P.R. China
Qiu-Fen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Xue-Mei Gao
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Corresponding Author(s) : Xue-Mei Gao
gao_xuemei@hotmail.com
Asian Journal of Chemistry,
Vol. 25 No. 17 (2013): Vol 25 Issue 17
A new pterocarpan, 3(S),4(S)-3'-methoxy-4'-hydroxy-7,8,-methylenedioxylpterocarpan (1), together with four known pterocarpan derivatives (2-5), were isolated from the whole plant of Clinopodium urticifolium. The structure of 1-5 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compound 1 was also evaluated for its cytotoxicity against five human tumor cell lines. The results revealed that compound 1 showed high cytotoxicity against PC3 cell with IC50 values of 3.5 μM and moderate cytotoxicities with IC50 valves 5-10 μM for other four tested cell lines.
