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Vol. 25 No. 15 (2013): Vol 25 Issue 15

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Flavonoids Derivatives from Arundina graminifolia and Their Cytotoxicity

https://doi.org/10.14233/ajchem.2013.14743A
Lidan Shu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Yanqiong Shen
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Liying Yang
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Xuemei Gao
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Qiu-Fen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China

Corresponding Author(s) : Xuemei Gao

gao_xuemei@hotmail.com

Asian Journal of Chemistry, Vol. 25 No. 15 (2013): Vol 25 Issue 15

Abstract

A new flavonoid, 3(S),4(S)-3',4'-dihydroxyl-7,8,-methylenedioxylpterocarpan (1), together with ten known flavonoids derivatives (2-11), were isolated from the whole plant of Arundina gramnifolia. The structure of compounds 1-11 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compound 1 was also evaluated for its cytotoxicity against five human tumor cell lines. The results revealed that compound 1 showed high cytotoxicity against HSY5Y cell with IC50 values of 2.2 μM and moderate cytotoxicities with IC50 valves 5-10 μM for other four tested cell lines.

Keywords

Arundina gramnifolia Flavonoids Cytotoxicity
Shu, L., Shen, Y., Yang, L., Gao, X., & Hu, Q.-F. (2013). Flavonoids Derivatives from Arundina graminifolia and Their Cytotoxicity. Asian Journal of Chemistry, 25(15), 8358–8360. https://doi.org/10.14233/ajchem.2013.14743A
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