Synthesis, Crystal Structure and DNA-Binding of a Novel Zinc(II) Complex with 2-(2-(1H-Benzo[d]imidazol-2-yl)phenoxy)acetic Acid

Abstract

A novel complex of [Zn(L)₂] (1) [HL = 2-(2-(1H-benzo[d]imidazol-2-yl)phenoxy)acetic acid] was synthesized and characterized by elemental analysis, IR and TG-DTG. Its crystal structure was determined by single crystal X-ray diffraction method. The complex crystallizes in orthorhombic with space group Pccn, cell parameters: a = 2.2030(2) nm, b = 0.70727(6) nm, c = 1.68856(1) nm, b = 90º, cell volume: V = 2.6310(4) nm³, number of molecules inside the cell: Z = 4, relative molecular mass: M_r = 599.89. The crystal structure shows that the zinc(II) ion is coordination with two oxygen atoms and two nitrogen atoms from two 2-(2-(1H-benzo[d]imidazol-2-yl)phenoxy) acetic acids, forming a distorted capped tetrahedron coordination geometry. In addition, the interaction of complex with DNA was also studied by ethidium bromide fluorescence spectroscopy. CCDC: 901910.