Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Jianhua Yao
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Lidan Shu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Liying Yang
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Xuemei Gao
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Qiu-Fen Hu
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, P.R. China
Corresponding Author(s) : Xuemei Gao
gao_xuemei@hotmail.com ; huqiufena@yahoo.com
Asian Journal of Chemistry,
Vol. 25 No. 14 (2013): Vol 25 Issue 14
A new phenylethanoid, 3,4-dihydroxyphenethyl-5-hydroxy-4-oxopentanoate (1), together with four known phenylethanoids (2-6), were isolated from the roots of Codonopsis cordifolioidea. Their structures were determined by means of HR ESI MS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compounds 1-6 were tested for their anti HIV-1 activities. Compounds 1 and 3 showed obvious anti HIV-1 activities with therapeutic index values above 50.
Shen, Y., Yao, J., Shu, L., Yang, L., Gao, X., & Hu, Q.-F. (2013). Phenylethanoids from the Roots of Codonopsis cordifolioidea and Their Anti HIV-1 Activities. Asian Journal of Chemistry, 25(14), 7888–7890. https://doi.org/10.14233/ajchem.2013.14677