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Vol. 25 No. 14 (2013): Vol 25 Issue 14

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Synthesis of Pyrazoleacrylic Acids and Their Derivatives

https://doi.org/10.14233/ajchem.2013.14670
Faryal Chaudhry
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Nadia Asif
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Muhammad Naeem Khan
Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Jorge Ribeiro
Secao de Quimica, Instituto Militar de Engenharia, Praia Vermelha, Rio de Janeiro, Brasil ; Deceased
Abdul Qayyum Ather
Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Sajila Hina
Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Munawar Ali Munawar
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Muhammad Nasrullah
Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Qura Tul Ain
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Farah Suhail
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan
Misbahul Ain Khan
Institute of Chemistry, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan ; Secao de Quimica, Instituto Militar de Engenharia, Praia Vermelha, Rio de Janeiro, Brasil ; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Corresponding Author(s) : Muhammad Naeem Khan

changwani_1@yahoo.com

Asian Journal of Chemistry, Vol. 25 No. 14 (2013): Vol 25 Issue 14

Abstract

Various pyrazole acrylic acid derivatives were obtained by the Knoevenagel condensation of pyrazole-4-carbaldehydes with ‘active methylene’ compounds. In the condensation reaction with malonic acid and cyanoacetic acid, decarboxylation of the resulting acids was not observed. The products were characterized through spectroscopic techniques and elemental analysis.

Keywords

Pyrazoles Knoevenagel condensation Pyrazole-4-carbaldehydes
Chaudhry, F., Asif, N., Naeem Khan, M., Ribeiro, J., Qayyum Ather, A., Hina, S., … Ain Khan, M. (2013). Synthesis of Pyrazoleacrylic Acids and Their Derivatives. Asian Journal of Chemistry, 25(14), 7879–7882. https://doi.org/10.14233/ajchem.2013.14670
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