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Vol. 25 No. 14 (2013): Vol 25 Issue 14

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Antifungal Activity of Aspirin Derivatives against Sclerotinia sclerotiorum

https://doi.org/10.14233/ajchem.2013.14599
Xuesong Wang
School of Physics and Chemistry, Xihua University, Chengdu 610039, P.R. China
Hui Feng
School of Bioengineering, Xihua University, Chengdu 610039, P.R. China
Ling Wang
School of Physics and Chemistry, Xihua University, Chengdu 610039, P.R. China
Xiaorong Tang
School of Physics and Chemistry, Xihua University, Chengdu 610039, P.R. China

Corresponding Author(s) : Xiaorong Tang

tangxiaorong0901@163.com

Asian Journal of Chemistry, Vol. 25 No. 14 (2013): Vol 25 Issue 14

Abstract

Two aspirin derivatives [2-(4-methylphenylcarbamoyl)phenyl acetate and 2-(4-methoxyphenylcarbamoyl)phenyl acetate] were synthesized by the ammonolysis of 2-(chlorocarbonyl)phenyl acetate. Their structure was confirmed by IR and 1H NMR. Their antifungal activity against Sclerotinia sclerotiorum has been determined in the laboratory. Results showed that they had good antifungal activity against Sclerotinia sclerotiorum. Their median effective concentrations (EC50) were 19.1 and 23.4 mg L-1, respectively.

Keywords

Antifungal activity 2-(4-Methoxyphenylcarbamoyl)phenyl acetate 2-(4-Methylphenylcarbamoyl)phenyl acetate
Wang, X., Feng, H., Wang, L., & Tang, X. (2013). Antifungal Activity of Aspirin Derivatives against Sclerotinia sclerotiorum. Asian Journal of Chemistry, 25(14), 8215–8216. https://doi.org/10.14233/ajchem.2013.14599
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