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Vol. 28 No. 5 (2016): Vol 28 Issue 5

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Solvent-Free Alkylation of 1,3-Dicarbonyl Compounds with Benzylic, Propargylic and Allylic Alcohols Catalyzed by La(NO3)3·6H2O

https://doi.org/10.14233/ajchem.2016.19621
Madala Subramanyam
Department of Chemistry, J.V.R. Government College, Sathupally, Khammam-507 303, India; Division of Chemistry, Department of Science & Humanities, Vignan's Foundation for Science, Technology and Research (VFSTR) University (Vignan’s University), Vadlamudi, Guntur-522 213, India
Koya Prabhakara Rao
Division of Chemistry, Department of Science & Humanities, Vignan's Foundation for Science, Technology and Research (VFSTR) University (Vignan’s University), Vadlamudi, Guntur-522 213, India
Ravi Varala
Polymer Department, Institute de Fisica de Sao Carlos, University of Sao Paulo, P.O. Box: 369/13560-970, Brazil
Mandava V. Basaveswara Rao
Department of Chemistry, Krishna University, Machilipatnam, Krishna-521001, India

Corresponding Author(s) : Koya Prabhakara Rao

kprao2005@gmail.com

Asian Journal of Chemistry, Vol. 28 No. 5 (2016): Vol 28 Issue 5

Abstract

An efficient and solvent free method for benzylation, propargylation and allylation of 1,3-dicarbonyl compounds with alcohols has been developed by using La(NO3)3·6H2O as water tolerable catalyst. The reaction was shown to proceed smoothly for various 1,3-dicarbonyl compounds with benzylic, propargylic and allylic alcohols including 10 allylic alcohols, without any solvent, providing a clean access to the desired products in short reaction times with good to excellent yields and high selectivity.

Keywords

Solvent-free Benzylic Propargylic Allylic alcohols 1,3-Dicarbonyl Alkylation La(NO3)3·6H2O
Subramanyam, M., Rao, K. P., Varala, R., & Basaveswara Rao, M. V. (2016). Solvent-Free Alkylation of 1,3-Dicarbonyl Compounds with Benzylic, Propargylic and Allylic Alcohols Catalyzed by La(NO3)3·6H2O. Asian Journal of Chemistry, 28(5), 1155–1160. https://doi.org/10.14233/ajchem.2016.19621
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