Institute of Chemical Industry of Forestry Products, CAF; Key Lab. of Biomass Energy and Material, Jiangsu Province; National Engineering Lab. for Biomass Chemical Utilization; Key and Lab. on Forest Chemical Engineering, SFA, Nanjing 210042, P.R. China
Jianling Xia
Institute of Chemical Industry of Forestry Products, CAF; Key Lab. of Biomass Energy and Material, Jiangsu Province; National Engineering Lab. for Biomass Chemical Utilization; Key and Lab. on Forest Chemical Engineering, SFA, Nanjing 210042, P.R. China ; Institute of Forest New Technology, CAF, Beijing 100091, P.R. China
Mei Wang
Institute of Chemical Industry of Forestry Products, CAF; Key Lab. of Biomass Energy and Material, Jiangsu Province; National Engineering Lab. for Biomass Chemical Utilization; Key and Lab. on Forest Chemical Engineering, SFA, Nanjing 210042, P.R. China
Xiaodong Tang
Institute of Chemical Industry of Forestry Products, CAF; Key Lab. of Biomass Energy and Material, Jiangsu Province; National Engineering Lab. for Biomass Chemical Utilization; Key and Lab. on Forest Chemical Engineering, SFA, Nanjing 210042, P.R. China
Lisha Gao
Quality, Safety and Environmental Department, Petrochina Hebei Marketing Company, Shijiazhuang 050000, Hebei Province, P.R. China
Yafeng Yang
Special Operation Division, The Third Engineering Company of CPP, Zhengzhou 451450, Henan Province, P.R. China
Corresponding Author(s) : Jianling Xia
xiajianling@126.com
Asian Journal of Chemistry,
Vol. 25 No. 12 (2013): Vol 25 Issue 12
In this paper, 4-(4-methylpent-3-enyl)cyclohex-4-ene-1,2-dicarboxamide was synthesized by b-myrcene through Diels-Alder reaction and ammonolysis reaction. The synthetic compound was proved to be the target product with the help of NMR, FT-IR and GC-MS. Diels-Alder reaction has been optimized under the following conditions: 150 ºC, reacting for 3 h, no catalyst and the production rate of 4-(4-methylpent-3-enyl)cyclohex-4-ene-1,2-dicarboxamide is 88.12 %, the selectivity is 97.49 %. Then get down to ammonolysis reaction under 0.4 MPa ammonia pressure for 18 h with methanol as the solvent and the production rate turned up to 88.7 %. At last, the test of the antibacterial activity of the target product showed optimistic to Staphylococcus aureus but passimistic to Escherichia coli.
Lian, J., Xia, J., Wang, M., Tang, X., Gao, L., & Yang, Y. (2013). Synthesis and Antibacterial Activity of 4-(4-Methylpent-3-enyl)cyclohex-4-ene-1,2-dicarboxamide. Asian Journal of Chemistry, 25(12), 6718–6720. https://doi.org/10.14233/ajchem.2013.14431
