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Chemical Compositions of Essential Oils of Different Parts and Extract of Achillea santolina L. from Iran
Corresponding Author(s) : Alireza Motavalizadehkakhky
Asian Journal of Chemistry,
Vol. 25 No. 11 (2013): Vol 25 Issue 11
Abstract
GC and GC-MS analysis of the isolated essential oils obtained by steam distillation from the flowers, leaves and stem of Achillea santolina L., known to have medicinal activity, collected from Iran. The constituents obtained by hexane-ether extraction of the aerial parts of Achillea santolina L. resulted in the identification of 48-59 constituents (96.1-98.0 % of the total oils and extract). Different parts of A. santolina were the valuable organs for the essential oil production representing a yield of 0.15-0.7 % (w/w). In the hydrodistilled oil of three parts and the extract of A. santolina, 1,8-cineole (3-5 %), camphor (3.8-5.1 %), terpinene-4-ol (4.0-7.1 %), fragranol (7.1-9.1 %), fragranyl acetate (20-37 %), a-terpinyl acetate (0.6-5.1 %), caryophyllene oxide (1.2-3.2 %), a-muurolol (1.1-3.6 %) and some alkanes, alkanoic acids and esters were principle components, also monoterpenes (7.1-9.1 %) and oxygenated monoterpenes (55.1-77.2 %) were dominant components.
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- N.S. Radulovic, P.D. Blagojevic, D. Skropeta, A.R. Zarubica, B.K. Zlatkovic and R.M. Palic, Nat. Prod. Commun., 5, 121 (2010).
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- U. Kastner, S. Sosa, M. Wolf, A. Tubaro, J. Jurenitsch and D.R. Loggia, Sci. Pharm., 61, 47 (1993).
- X.T. Si, M.L. Zhang, Q.W. Shi and H. Kiyota, Chem. Biodivers, 3, 1163 (2006).
- N. Celik and H.A. Akpulat, Kew Bull., 63, 485 (2008).
- N. Bezic, M. Skocibucic, V. Dunkic and A. Radonic, Phytother. Res., 17, 1037 (2003).
- A.M. El-Shazly, S.S. Hafez and M. Wink, Pharmazie, 59, 226 (2004).
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References
N.S. Radulovic, P.D. Blagojevic, D. Skropeta, A.R. Zarubica, B.K. Zlatkovic and R.M. Palic, Nat. Prod. Commun., 5, 121 (2010).
B. Benedek, K. Rothwangl-Wiltschnigg, E. Rozema, N. Gjoncaj, G. Reznicek, J. Jurenitsch, B. Kopp and S. Glasl, Pharmazie, 63, 23 (2008).
E. Nemeth and J. Bernath, Curr. Pharm. Design, 14, 3151 (2008).
V. Mozaffarian, A Dictionary of Iranian Plant Names, Farhang Moaser Publishers, Tehran, Iran (2007).
T. Aburjai and M. Hudaib, Pharmacog Mag, 2, 191 (2006).
O. Toncer, S. Basbag, S. Karaman, E. Diraz and M. Basbag, Int. J. Agric. Biol., 12, 527 (2010).
A. DerMarderosian, The Review of Natural Products, Facts and Comparison press, Missouri, p. 636 (2001).
E. Yesilada, G. Honda, E. Sezik, M. Tabata, K. Goto and Y. Ikeshiro, J. Ethnopharmacol., 39, 31 (1993).
T. Baytop, Phytotherapy in Turkey, Nobel T.P. Kitabevleri Ltd., Sti., Istanbul, Tureky, edn. 2 (1995).
S. Konyalioglu and C. Karamenderes, J. Ethnopharmacol., 102, 221 (2005).
J. Hubik, Obecná farmakognosie (II. díl)-Sekundární látky, Praha, p. 275 (1978).
U. Kastner, S. Sosa, M. Wolf, A. Tubaro, J. Jurenitsch and D.R. Loggia, Sci. Pharm., 61, 47 (1993).
X.T. Si, M.L. Zhang, Q.W. Shi and H. Kiyota, Chem. Biodivers, 3, 1163 (2006).
N. Celik and H.A. Akpulat, Kew Bull., 63, 485 (2008).
N. Bezic, M. Skocibucic, V. Dunkic and A. Radonic, Phytother. Res., 17, 1037 (2003).
A.M. El-Shazly, S.S. Hafez and M. Wink, Pharmazie, 59, 226 (2004).
M. Azizi, R. Chizzola,A. Ghani and F. Oroojalian, Nat. Prod. Commun., 5, 283 (2010).
K. Javidnia, R. Miri and H. Sadeghpour, Daru, 12, 63 (2004).
S.M. Khafagy and L. El-Faraty, J. Pharm. Sci. (UAR), 11, 239 (1970).
S. Afsharypour, S. Asgary and G.B. Lockwood, Planta Med., 62, 77 (1996).
R.P. Adams, Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry, Allured Publishing Co. Carol Stream, Illinois, edn. 4 (2007).