Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Mononuclear Cobalt(II) Complex with 4-Chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester

Suo-Ping Xu; Tuan-Jie Li; Guo Xu; Yuan Pei

doi:10.14233/ajchem.2013.14269

Issue

Vol. 25 No. 11 (2013): Vol 25 Issue 11

Issue Published : May 18, 2013

This work is licensed under a Creative Commons Attribution 4.0 International License.

Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Mononuclear Cobalt(II) Complex with 4-Chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester

https://doi.org/10.14233/ajchem.2013.14269

Suo-Ping Xu

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P.R. China ; School of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221008, P.R. China

Tuan-Jie Li

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P.R. China

Guo Xu

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P.R. China

Yuan Pei

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P.R. China

Corresponding Author(s) : Suo-Ping Xu

xsp62@jsnu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 11 (2013): Vol 25 Issue 11
Article Published : June 6, 2013

Abstract

One mononuclear complex has been designed and synthesized by a b-diketone ligand 4-chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester (L) with CoCl₂·6H₂O in microwave radiation assistance. The complex was characterized by X-ray crystallography, confirming that the central cobalt(II) was coordinated by four oxygens from two b-diketone ligand and two oxygens from two ethanols. The complex was assayed for in vitro antibacterial (B. subtilis, S. aureus, S. faecalis, P. aeruginosa, E. coli and E. cloacae) activities and showed better antimicrobial activity against Gram positive strains than Gram negative strains.

Keywords

Microwave solid phase synthesis Mononuclear cobalt(II) complex Antibacterial activity β-Diketone ligand

Xu, S.-P., Li, T.-J., Xu, G., & Pei, Y. (2013). Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Mononuclear Cobalt(II) Complex with 4-Chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester. Asian Journal of Chemistry, 25(11), 6105–6108. https://doi.org/10.14233/ajchem.2013.14269

Download Citation

References

M. Sakkarapalayam and S.A. Indrapal, J. Org. Chem., 71, 349 (2006).
L. Gong, R. Leung-Toung and T.T. Tidwell, J. Org. Chem., 55, 3634 (1990).
G. Blaskó, L. Xun and G.A. Cordell, J. Nat. Prod., 51, 60 (1988).
A.R. Katritzky, Z.-Q. Wang, M.-Y. Wang, C.R. Wilkerson, C.D. Hall and N.G. Akhmedov, J. Org. Chem., 69, 6617 (2004).
S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011).
R. Kumar and Y.C. Joshi, J. Serb. Chem. Soc., 73, 937 (2008).
L. Li, P.-J. Cai, D. Xu, Q.-X. Guo and S. Xue, J. Org. Chem., 72, 8131 (2007).
K. Singletary, C. MacDonald, M. Iovinelli, C. Fisher and M. Wallig, Carcinogenesis, 19, 1039 (1998).
X. Zhang, Z.-C. Li, N. Xu, K.-B. Li, S. Lin, F.-Z. Lu, F.-S. Du and F.-M. Li, Tetrahedron Lett., 47, 2623 (2006).
D. Teixeira, T. Lalot, M. Brigodiot and E. Maréchal, Macromolecules, 32, 70 (1999).
A. Joshi, S. Verma, R.B. Gaur and R.R. Sharma, Bioinorg. Chem. Appl., 3, 201 (2005).
C.L. Modenbach, F.R. Fronczek, E.W. Berg and T.C. Taylor, Inorg. Chem., 22, 4083 (1983).
G. Xu, S.-P. Xu, J.-X. Shu, Y. Pei, W.-X. Su and J. Xuzhou, Norm. Univ.: Nat. Sci. Ed., 29, 66 (2011).
G.M. Sheldrick SHELXL-97, Program for the Refinement of Crystal Structures, University of Göttingen, Germany (1977).
J. Meletiadis, J.F. Meis, J.W. Mouton, J.P. Donnelly and P.E. Verweij, J. Clin. Microbiol., 38, 2949 (2000).
K. Nakamato, Infrared Spectra of Inorganic and Coordination Compounds, Wiley, New York (1964).
S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011).
J.-M. Li, J.-Z. Li, H.-Q. Zhang and L.-Y. Xu, Inorg. Chem. Commun., 13, 573 (2010).
J.K. Clegg, D.J. Bray, K. Gloe, K. Gloe, M.J. Hayter, K.A. Jolliffe, G.A. Lawrance, G.V. Meehan, J.C. McMurtrie, L.F. Lindoy and M. Wenzel, J. Chem. Soc., Dalton Trans., 1719 (2007).
R.V. Singh, P. Chaudhary, S. Chauhan and M. Swami, Spectrochim. Acta A, 72, 260 (2009).
M. Nath, S. Pokharia, X. Song, G. Eng, M. Gielen, M. Kemmer, M. Biesemans, R. Willem and D. De Vos, Appl. Organomet. Chem., 17, 305 (2003).

References

M. Sakkarapalayam and S.A. Indrapal, J. Org. Chem., 71, 349 (2006).

L. Gong, R. Leung-Toung and T.T. Tidwell, J. Org. Chem., 55, 3634 (1990).

G. Blaskó, L. Xun and G.A. Cordell, J. Nat. Prod., 51, 60 (1988).

A.R. Katritzky, Z.-Q. Wang, M.-Y. Wang, C.R. Wilkerson, C.D. Hall and N.G. Akhmedov, J. Org. Chem., 69, 6617 (2004).

S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011).

R. Kumar and Y.C. Joshi, J. Serb. Chem. Soc., 73, 937 (2008).

L. Li, P.-J. Cai, D. Xu, Q.-X. Guo and S. Xue, J. Org. Chem., 72, 8131 (2007).

K. Singletary, C. MacDonald, M. Iovinelli, C. Fisher and M. Wallig, Carcinogenesis, 19, 1039 (1998).

X. Zhang, Z.-C. Li, N. Xu, K.-B. Li, S. Lin, F.-Z. Lu, F.-S. Du and F.-M. Li, Tetrahedron Lett., 47, 2623 (2006).

D. Teixeira, T. Lalot, M. Brigodiot and E. Maréchal, Macromolecules, 32, 70 (1999).

A. Joshi, S. Verma, R.B. Gaur and R.R. Sharma, Bioinorg. Chem. Appl., 3, 201 (2005).

C.L. Modenbach, F.R. Fronczek, E.W. Berg and T.C. Taylor, Inorg. Chem., 22, 4083 (1983).

G. Xu, S.-P. Xu, J.-X. Shu, Y. Pei, W.-X. Su and J. Xuzhou, Norm. Univ.: Nat. Sci. Ed., 29, 66 (2011).

G.M. Sheldrick SHELXL-97, Program for the Refinement of Crystal Structures, University of Göttingen, Germany (1977).

J. Meletiadis, J.F. Meis, J.W. Mouton, J.P. Donnelly and P.E. Verweij, J. Clin. Microbiol., 38, 2949 (2000).

K. Nakamato, Infrared Spectra of Inorganic and Coordination Compounds, Wiley, New York (1964).

S.-P. Xu, B.-F. Ruan, Q.-Y. Pan and R.-T. Hu, J. Coord. Chem., 64, 2489 (2011).

J.-M. Li, J.-Z. Li, H.-Q. Zhang and L.-Y. Xu, Inorg. Chem. Commun., 13, 573 (2010).

J.K. Clegg, D.J. Bray, K. Gloe, K. Gloe, M.J. Hayter, K.A. Jolliffe, G.A. Lawrance, G.V. Meehan, J.C. McMurtrie, L.F. Lindoy and M. Wenzel, J. Chem. Soc., Dalton Trans., 1719 (2007).

R.V. Singh, P. Chaudhary, S. Chauhan and M. Swami, Spectrochim. Acta A, 72, 260 (2009).

M. Nath, S. Pokharia, X. Song, G. Eng, M. Gielen, M. Kemmer, M. Biesemans, R. Willem and D. De Vos, Appl. Organomet. Chem., 17, 305 (2003).

Issue

Vol. 25 No. 11 (2013): Vol 25 Issue 11

Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Mononuclear Cobalt(II) Complex with 4-Chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester

Corresponding Author(s) : Suo-Ping Xu

Abstract

Keywords

Full Article

Download Citation

References

Table Of Contents